Department of Dental Hygiene, College of Medical Science, Konyang University, Daejeon, Republic of Korea.
Department and Research Institute of Dental Biomaterials and Bioengineering, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Clin Oral Investig. 2022 Aug;26(8):5301-5312. doi: 10.1007/s00784-022-04498-7. Epub 2022 Apr 22.
This study aimed to evaluate the effects of 30% hydrogen peroxide (HP) solution containing various contents of 45S5 bioactive glass (BAG) on whitening efficacy and enamel surface properties after simulating the clinical bleaching procedure.
A total of 60 bovine enamel specimens discolored with black tea were divided into five groups treated with distilled water (DW), HP, 0.01 wt.% BAG + HP, 1.0 wt.% BAG + HP, and 20.0 wt.% BAG + HP (n = 12). The pH change was observed for 20 min immediately after mixing the experimental solutions, which were applied for 20 min/week, at 37 °C over 21 days. Color, gloss, roughness, microhardness, and micromorphology measurements were conducted before and after bleaching treatment.
All groups containing BAG experienced an increase in pH from 3.5 to 5.5 in less than 1 min, and the final pH increased as the BAG content increased. The ΔE of all experimental groups was significantly higher than that of the DW group (p < 0.05), but there were no significant differences between different BAG contents (p > 0.05). Gloss significantly decreased in all experimental groups compared to the DW group, and the increased BAG content had significantly affected the decrease in gloss (p < 0.05). There was no statistical difference in surface roughness (p > 0.05), but hardness increased significantly with BAG content after bleaching treatment (p < 0.05).
HP containing 45S5 BAG showed efficacy in tooth whitening. Also, the pH value of the HP remained acidic near 3.5 for 20 min, while the HP containing the 45S5 BAG showed an increase in pH, which inhibited the demineralization of the enamel surface, and maintained the surface morphology.
These novel materials are promising candidates to minimize enamel surface damage caused by HP during bleaching procedure in dental clinic.
本研究旨在评估含有不同含量 45S5 生物活性玻璃(BAG)的 30%双氧水(HP)溶液在模拟临床漂白程序后对美白效果和牙釉质表面性能的影响。
将 60 个用红茶染色的牛牙釉质标本分为 5 组,分别用蒸馏水(DW)、HP、0.01wt.% BAG+HP、1.0wt.% BAG+HP 和 20.0wt.% BAG+HP 处理(n=12)。混合实验溶液后立即观察 20 分钟内 pH 值的变化,在 37°C 下每周应用 20 分钟,共 21 天。在漂白处理前后进行颜色、光泽度、粗糙度、显微硬度和微观形貌测量。
所有含 BAG 的组在不到 1 分钟内 pH 值从 3.5 增加到 5.5,且最终 pH 值随 BAG 含量增加而增加。所有实验组的 ΔE 均显著高于 DW 组(p<0.05),但不同 BAG 含量之间无显著差异(p>0.05)。与 DW 组相比,所有实验组的光泽度均显著降低,且 BAG 含量增加显著影响光泽度降低(p<0.05)。表面粗糙度无统计学差异(p>0.05),但漂白处理后 BAG 含量增加显著提高了硬度(p<0.05)。
含 45S5 BAG 的 HP 具有牙齿美白效果。此外,HP 的 pH 值在 20 分钟内仍保持在近 3.5 的酸性,而含 45S5 BAG 的 HP 则显示 pH 值增加,抑制了牙釉质表面脱矿,保持了表面形态。
这些新型材料有望成为减少牙科临床漂白过程中 HP 对牙釉质表面损伤的候选材料。