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[一例巨细胞显微镜下结肠炎?]

[A case of giant cell microscopic colitis?].

作者信息

Duclos Juliette, Kussaibi Haitham, Pacault Vincent, Roussel Hélène, Sandid Wissam, Janin Anne, Bertheau Philippe

机构信息

Service de pathologie, hôpital Saint-Louis, AP-HP, 1, avenue Claude-Vellefaux, 75010 Paris, France.

出版信息

Ann Pathol. 2008 Dec;28(6):501-3. doi: 10.1016/j.annpat.2008.09.045. Epub 2008 Nov 17.

Abstract

Microscopic colitis is the most common cause of chronic watery diarrhea, with normal mucosal appearance during colonoscopy. The diagnosis is made by pathological examination of biopsy specimens showing colitis with normal architecture of the mucosa. The two most frequent forms of microscopic colitis are lymphocytic colitis and collagenous colitis, but other atypical variants have been described. We report a case of lymphocytic colitis with multinucleated large cells and we discuss a variant of giant cells microscopic colitis.

摘要

显微镜下结肠炎是慢性水样腹泻最常见的病因,结肠镜检查时黏膜外观正常。诊断通过对活检标本进行病理检查作出,显示黏膜结构正常的结肠炎。显微镜下结肠炎最常见的两种类型是淋巴细胞性结肠炎和胶原性结肠炎,但也有其他非典型变体的描述。我们报告一例伴有多核大细胞的淋巴细胞性结肠炎病例,并讨论巨细胞显微镜下结肠炎的一种变体。

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