Beard Jonathan D
Sheffield Vascular Institute, Northern General Hospital, Sheffield, United Kingdom.
J Vasc Surg. 2008 Dec;48(6 Suppl):11S-16S. doi: 10.1016/j.jvs.2008.08.036.
This review considers the roles of endovascular and open surgery for critical lower limb ischemia. The TransAtlantic Inter-Society Consensus document offers sensible guidelines for the treatment of both suprainguinal and infrainguinal disease. For bilateral/diffuse suprainguinal disease, aortobifemoral bypass remains the best option, but great care should be taken in this new era of hospital-acquired infection. Unilateral iliac occlusions should be treated by primary stenting, but an iliofemoral or femorofemoral bypass may be the best option when the disease extends down into the common femoral artery. Stents may reduce the risk of embolization in iliac stenoses but probably confer no benefit in long-term patency. Iliac stenoses should be treated by angioplasty, with stents reserved for flow-limiting complications. Although infrainguinal bypass surgery is in decline, probably due to better medical treatment and more endovascular intervention, bypass using autologous saphenous vein remains the gold standard. In the absence of leg veins, arm vein should be considered. Prosthetic grafts should be used as a last resort, and only with a venous cuff. The long-term results of the Bypass Versus Angioplasty in Severe Ischemia of the Leg (BASIL) trial favor surgery rather than angioplasty if there is a good vein and the patient is fit. Further randomized studies of infrainguinal stenting vs bypass are required. Some patients with critical lower limb ischemia are best treated by analgesia or primary amputation.
本综述探讨了血管内手术和开放手术在治疗严重下肢缺血中的作用。《跨大西洋跨学会共识》文件为治疗腹股沟上和腹股沟下疾病提供了合理的指导原则。对于双侧/弥漫性腹股沟上疾病,主动脉双股动脉旁路移植术仍是最佳选择,但在医院获得性感染的新时代应格外小心。单侧髂动脉闭塞应采用一期支架置入术治疗,但当疾病延伸至股总动脉时,髂股或股股动脉旁路移植术可能是最佳选择。支架可降低髂动脉狭窄时的栓塞风险,但对长期通畅率可能无益处。髂动脉狭窄应采用血管成形术治疗,支架仅用于治疗血流受限的并发症。尽管腹股沟下旁路手术的应用在减少,这可能是由于更好的药物治疗和更多的血管内介入治疗,但使用自体大隐静脉进行旁路移植术仍然是金标准。在没有腿部静脉可用的情况下,应考虑使用手臂静脉。人工血管应作为最后手段使用,且仅用于带静脉套的情况。如果有良好的静脉且患者身体状况适宜,腿部严重缺血的旁路移植术与血管成形术比较(BASIL)试验的长期结果支持手术而非血管成形术。需要进一步对腹股沟下支架置入术与旁路移植术进行随机研究。一些严重下肢缺血患者通过镇痛或一期截肢治疗效果最佳。