Hum Fertil (Camb). 2008 Dec;11(4):201-10. doi: 10.1080/14647270802563816.
This article updates the 1999 British Andrology Society (BAS) guidelines for the screening of sperm donors and the 2000 British Fertility Society (BFS) guidelines for the screening of egg and embryo donors and combines the new recommendations into a single document. This was achieved by a multidisciplinary working group composed of representatives from the Association of Biomedical Andrologists, the Association of Clinical Embryologists, the BAS, the BFS and the Royal College of Obstetricians and Gynecologists. The major changes to the guidelines include a requirement to consider a donor's risk of transmissible spongiform encephalopathies and the recommendation to screen for human T cell lymphotropic viruses 1 and 2. The role of nucleic amplification tests for the detection of blood borne viruses such as HIV is discussed, but it remains the recommendation that this be achieved by serological testing to detect antibody or antigen as appropriate with a quarantine period of 180 days.
本文更新了1999年英国男科学会（BAS）关于精子捐献者筛查的指南以及2000年英国生育学会（BFS）关于卵子和胚胎捐献者筛查的指南，并将新的建议合并为一份文件。这是由一个多学科工作组完成的，该工作组由生物医学男科学家协会、临床胚胎学家协会、BAS、BFS以及皇家妇产科学院的代表组成。指南的主要变化包括要求考虑捐献者感染可传播性海绵状脑病的风险，以及建议筛查人类嗜T细胞病毒1型和2型。文中讨论了核酸扩增检测在检测如HIV等血源病毒方面的作用，但仍然建议通过血清学检测来适当检测抗体或抗原，并设置180天的检疫期来实现这一目的。
