Szpinda M
Department of Normal Anatomy, the Ludwik Rydygier Collegium Medicum, Poland.
Folia Morphol (Warsz). 2008 Nov;67(4):240-4.
This study defines the growth patterns for the external diameters of the pulmonary arteries in human foetuses, including relationships with sex, side of body (right-left) and foetal age. Using anatomical dissection, digital-image analysis (system of Leica Q Win Pro 16) and statistical analysis (ANOVA, regression analysis), a range of external diameters for the right and left pulmonary arteries in 128 spontaneously aborted human foetuses aged 15-34 weeks was examined. No significant gender differences were found (p > 0.05). In the examined age range the values of the external diameter of the right pulmonary artery ranged from 0.97 +/- 0.24 to 2.95 +/- 0.89 mm, according to the linear function y = -0.7753 + 0.1148 x +/- 0.4580 (r = 0.83; p < 0.001). The values of the external diameter of the left pulmonary artery ranged from 0.88 +/- 0.25 to 2.63 +/- 0.80 mm, in accordance with the linear relationship y = -0.6228 + 0.1007 x +/- 0.4280 (r = 0.81; p < 0.001). The external diameters of the right pulmonary artery were greater than those of the left pulmonary artery (p < 0.001). Parallel to the increase in the values of the external diameters of both the pulmonary arteries, the pulmonary artery-to-ascending aorta diameter ratio (the relative diameter of the pulmonary artery) decreased with advanced foetal age from 0.46 +/- 0.10 to 0.43 +/- 0.13 for the right pulmonary artery, and from 0.43 +/- 0.10 to 0.39 +/- 0.12 for the left one. The growth curves generated may be useful as reference data for foetal diagnosis.
本研究确定了人类胎儿肺动脉外径的生长模式，包括与性别、身体侧别（右-左）和胎儿年龄的关系。通过解剖、数字图像分析（徕卡Q Win Pro 16系统）和统计分析（方差分析、回归分析），对128例15至34周自然流产的人类胎儿的左右肺动脉外径范围进行了研究。未发现显著的性别差异（p>0.05）。在所研究的年龄范围内，右肺动脉外径值根据线性函数y = -0.7753 + 0.1148x +/- 0.4580，范围从0.97 +/- 0.24至2.95 +/- 0.89毫米（r = 0.83；p<0.001）。左肺动脉外径值根据线性关系y = -0.6228 + 0.1007x +/- 0.4280，范围从0.88 +/- 0.25至2.63 +/- 0.80毫米（r = 0.81；p<0.001）。右肺动脉外径大于左肺动脉外径（p<0.001）。随着两条肺动脉外径值的增加，肺动脉与升主动脉直径比（肺动脉相对直径）随着胎儿年龄的增加而降低，右肺动脉从0.46 +/- 0.10降至0.43 +/- 0.13，左肺动脉从0.43 +/- 0.10降至0.39 +/- 0.12。生成的生长曲线可作为胎儿诊断的参考数据。
