Kothmann E, Danjoux G, Owen S J, Parry A, Turley A J, Batterham A M
Department of Anaesthesia, James Cook University Hospital, Middlesbrough, UK.
Anaesthesia. 2009 Jan;64(1):9-13. doi: 10.1111/j.1365-2044.2008.05690.x.
Anaerobic threshold (AT), determined by cardiopulmonary exercise testing (CPET), is a well-documented measure of pre-operative fitness, although its reliability in patient populations is uncertain. Our aim was to assess the reliability of AT measurement in patients with abdominal aortic aneurysms. Eighteen patients were recruited. CPET was performed four times over a 6-week period. We examined shifts in the mean AT to evaluate systematic bias with random measurement error assessed using typical within-patient error and intraclass correlation coefficient (ICC, 3,1) statistics. There was no significant or clinically substantial change in mean AT across the tests (p = 0.68). The typical within-patient error expressed as a percentage coefficient of variation was 10% (95% CI, 8-13%), with an ICC of 0.74 (95% CI, 0.55-0.89). We consider the reliability of the AT to be acceptable, supporting its clinical validity and utility as an objective marker of pre-operative fitness in this population.
通过心肺运动试验(CPET)测定的无氧阈(AT)是一种有充分文献记载的术前体能指标,尽管其在患者群体中的可靠性尚不确定。我们的目的是评估腹主动脉瘤患者AT测量的可靠性。招募了18名患者。在6周内进行了4次CPET。我们检查了平均AT的变化,以评估系统偏差,并使用典型的患者内误差和组内相关系数(ICC,3,1)统计量评估随机测量误差。各次测试的平均AT没有显著或临床上的实质性变化(p = 0.68)。以变异系数百分比表示的典型患者内误差为10%(95%CI,8 - 13%),ICC为0.74(95%CI,0.55 - 0.89)。我们认为AT的可靠性是可以接受的,这支持了其作为该人群术前体能客观指标的临床有效性和实用性。