Sinclair R C F, Danjoux G R, Goodridge V, Batterham A M
Department of Anaesthesia, The James Cook University Hospital, University of Teesside, Middlesbrough, UK.
Anaesthesia. 2009 Nov;64(11):1192-5. doi: 10.1111/j.1365-2044.2009.06074.x.
The variability between observers in the interpretation of cardiopulmonary exercise tests may impact upon clinical decision making and affect the risk stratification and peri-operative management of a patient. The purpose of this study was to quantify the inter-reader variability in the determination of the anaerobic threshold (V-slope method). A series of 21 cardiopulmonary exercise tests from patients attending a surgical pre-operative assessment clinic were read independently by nine experienced clinicians regularly involved in clinical decision making. The grand mean for the anaerobic threshold was 10.5 ml O(2).kg body mass(-1).min(-1). The technical error of measurement was 8.1% (circa 0.9 ml.kg(-1).min(-1); 90% confidence interval, 7.4-8.9%). The mean absolute difference between readers was 4.5% with a typical random error of 6.5% (6.0-7.2%). We conclude that the inter-observer variability for experienced clinicians determining the anaerobic threshold from cardiopulmonary exercise tests is acceptable.
观察者在解读心肺运动试验时的差异可能会影响临床决策,并对患者的风险分层和围手术期管理产生影响。本研究的目的是量化读者间在确定无氧阈值(V 斜率法)时的变异性。来自外科术前评估门诊患者的 21 份心肺运动试验系列报告由九名经常参与临床决策的经验丰富的临床医生独立解读。无氧阈值的总体均值为 10.5 ml O₂·kg 体重⁻¹·min⁻¹。测量的技术误差为 8.1%(约 0.9 ml·kg⁻¹·min⁻¹;90% 置信区间,7.4 - 8.9%)。读者之间的平均绝对差异为 4.5%,典型随机误差为 6.5%(6.0 - 7.2%)。我们得出结论,经验丰富的临床医生通过心肺运动试验确定无氧阈值时,观察者间的变异性是可以接受的。