Southampton University Hospitals NHS Trust, Southampton, UK.
Anaesthesia. 2011 Aug;66(8):659-66. doi: 10.1111/j.1365-2044.2011.06714.x. Epub 2011 Jun 24.
The oxygen uptake efficiency slope is a measure of cardiopulmonary fitness, that can be obtained from a sub-maximal cardiopulmonary exercise test. It has been evaluated in medical patients but its reliability in surgical populations remains uncertain. We conducted a test-retest study with the aim of establishing the reliability of the oxygen uptake efficiency slope in relation to that of the anaerobic threshold and peak oxygen uptake, in general surgical patients. Twenty-six patients over 60 years old completed two symptom-limited, incremental cycle ergometry tests within 7 days. The mean (SD) anaerobic threshold was 13.0 (3.0) mlO(2) .kg(-1) .min(-1) . There were no significant differences between mean test and retest values of anaerobic threshold (p = 0.50), peak oxygen uptake (p = 0.76) or oxygen uptake efficiency slope (p = 0.42). Reliability coefficients (95% CI) for the anaerobic threshold, oxygen uptake efficiency slope and peak oxygen uptake were 66.7% (45.3-87.9%), 89.0% (81.0-96.9%) and 91.7% (85.7-97.8%), respectively. The oxygen uptake efficiency slope was determined easily in all patients and found to have excellent reliability. Its clinical utility in determining pre-operative fitness warrants further evaluation.
摄氧量效率斜率是心肺功能的一种衡量标准,可以通过次最大心肺运动试验获得。它已在医学患者中进行了评估,但在外科患者中的可靠性仍不确定。我们进行了一项测试-再测试研究,旨在确定摄氧量效率斜率与无氧阈和峰值摄氧量的可靠性,在一般外科患者中。26 名 60 岁以上的患者在 7 天内完成了两次症状限制、递增的循环测力计测试。无氧阈的平均值(SD)为 13.0(3.0)mlO(2).kg(-1).min(-1) 。无氧阈的平均值(p = 0.50)、峰值摄氧量(p = 0.76)或摄氧量效率斜率(p = 0.42)的测试值和再测试值之间没有显著差异。无氧阈、摄氧量效率斜率和峰值摄氧量的可靠性系数(95%CI)分别为 66.7%(45.3-87.9%)、89.0%(81.0-96.9%)和 91.7%(85.7-97.8%)。摄氧量效率斜率在所有患者中都很容易确定,并且发现其可靠性非常好。其在确定术前适应性方面的临床应用价值需要进一步评估。