Oscier C D, Milner Q J W
South West School of Anaesthesia, Department of Anaesthetics, Royal Cornwall Hospital, Truro TR13LJ, UK.
Anaesthesia. 2009 Jan;64(1):65-72. doi: 10.1111/j.1365-2044.2008.05674.x.
This article is a review of the peri-operative use of paracetamol. It reviews the pharmacology of paracetamol, highlighting new information about the mechanism of action, and examines its therapeutic use in the peri-operative period, focusing on efficacy, route of administration, and the use of a loading dose to improve early postoperative analgesia.
本文是对扑热息痛围手术期应用的综述。它回顾了扑热息痛的药理学,着重介绍了有关作用机制的新信息,并研究了其在围手术期的治疗应用,重点关注疗效、给药途径以及使用负荷剂量以改善术后早期镇痛。