Sevón Liisi, Laine Merja A, Karjalainen Sára, Doroguinskaia Anguelina, Helenius Hans, Kiss Endre, Lehtonen-Veromaa Marjo
Department of Periodontology, Institute of Dentistry, University of Turku, Finland.
Open Dent J. 2008;2:89-92. doi: 10.2174/1874210600802010089. Epub 2008 Jun 11.
As relatively little is known about the effect of age on salivary electrolytes we studied the composition of saliva as function of age to provide reference values for healthy non-smoking women. All non-medicated and non-smoking 30-59-year-old subjects (n=255) selected from among 1030 women participating in a screening program formed the material of the present study. Salivary calcium, inorganic phosphate, magnesium, sodium, potassium, protein and flow-rate of stimulated whole saliva were measured. We found age-related changes in salivary calcium and phosphate concentrations (p=0.001 and p=0.004, respectively, one-way ANOVA). Peak values occurred at around 50-54 years of age. Age had no effect on flow-rate, magnesium, sodium, potassium or proteins. The concentration of sodium correlated positively, while phosphate, potassium, magnesium and protein correlated negatively with the salivary flow-rate. Calcium was the only electrolyte which had no association with flow-rate. Our study provides reference values for salivary electrolytes of 30-59-year-old women.
由于关于年龄对唾液电解质的影响所知甚少，我们研究了唾液成分随年龄的变化情况，以便为健康的不吸烟女性提供参考值。从参与筛查项目的1030名女性中选取的所有未用药且不吸烟的30至59岁受试者（n = 255）构成了本研究的材料。测量了唾液钙、无机磷酸盐、镁、钠、钾、蛋白质以及刺激后的全唾液流速。我们发现唾液钙和磷酸盐浓度存在与年龄相关的变化（分别为p = 0.001和p = 0.004，单因素方差分析）。峰值出现在50至54岁左右。年龄对流速、镁、钠、钾或蛋白质没有影响。钠的浓度呈正相关，而磷酸盐、钾、镁和蛋白质与唾液流速呈负相关。钙是唯一与流速无关的电解质。我们的研究为30至59岁女性的唾液电解质提供了参考值。
