Häntzschel Nadine, Hund Rolf-Dieter, Hund Heike, Schrinner Marc, Lück Christian, Pich Andrij
Department of Macromolecular Chemistry and Textile Chemistry, Technische Universität Dresden, Dresden, Germany.
Macromol Biosci. 2009 May 13;9(5):444-9. doi: 10.1002/mabi.200800219.
In the present work, we have used aqueous microgels as containers for the deposition of silver nanoparticles (AgNPs). It has been shown that AgNPs can be effectively incorporated in the microgel interior during the in situ reduction of silver ions. Obtained hybrid microgels with variable AgNPs loading (from 1 to 12 wt.-%) have been used as antibacterial agents for two bacteria types. The experimental results indicate that porous microgel structure allows the release of the silver ions from the AgNPs surface into an aqueous phase. This ensures effective reduction in the number of bacterial colonies in test plates and complete bacteria killing. The antibacterial efficiency of the microgel particles increases with AgNPs loading.
在本研究中，我们使用了水性微凝胶作为银纳米颗粒（AgNPs）沉积的容器。研究表明，在银离子原位还原过程中，AgNPs能够有效地掺入微凝胶内部。所获得的具有可变AgNPs负载量（1至12重量％）的混合微凝胶已被用作两种细菌类型的抗菌剂。实验结果表明，多孔微凝胶结构允许银离子从AgNPs表面释放到水相中。这确保了测试平板中细菌菌落数量的有效减少和细菌的完全杀灭。微凝胶颗粒的抗菌效率随AgNPs负载量的增加而提高。
