Truong Hong M, Kellogg Timothy, Schwarcz Sandra, Delgado Viva, Grant Robert M, Louie Brian, Ngo Houston, McFarland Willi
Center for AIDS Prevention Studies, University of California, San Francisco, 50 Beale Street, Suite 1300, San Francisco, CA 94105, USA.
J Travel Med. 2008 Nov-Dec;15(6):454-6. doi: 10.1111/j.1708-8305.2008.00245.x.
We assessed the potential for international transmission of primary drug resistance among men who have sex with men newly diagnosed with human immunodeficiency virus (HIV) (n = 64) during the period in which they were unaware of their infection. During their exposure period, 55% of participants lived or traveled outside of the United States, and 59% had foreign-born sexual partners. Eighteen participants (28%) were classified as recently infected with HIV. Primary HIV-1 drug resistance was detected in eight participants (13%), four of whom were recently infected. Given the high frequency of international travel and prevalence of primary HIV-1 drug resistance among study participants, prevention strategies should incorporate specific counseling on risk of cross-border transmission.
我们评估了在新诊断出感染人类免疫缺陷病毒（HIV）的男男性行为者（n = 64）未意识到自身感染期间，原发性耐药国际传播的可能性。在其暴露期，55%的参与者在美国境外生活或旅行，59%有外国出生的性伴侣。18名参与者（28%）被归类为近期感染HIV。在8名参与者（13%）中检测到原发性HIV-1耐药，其中4人是近期感染。鉴于研究参与者国际旅行频率高以及原发性HIV-1耐药的流行情况，预防策略应纳入关于跨境传播风险的具体咨询。
