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一个综合性的韩国生物多样性和遗传信息检索系统。

An integrated Korean biodiversity and genetic information retrieval system.

作者信息

Lim Jeongheui, Bhak Jong, Oh Hee-Mock, Kim Chang-Bae, Park Yong-Ha, Paek Woon Kee

机构信息

Korean BioInformation Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 305-806, Korea.

出版信息

BMC Bioinformatics. 2008 Dec 12;9 Suppl 12(Suppl 12):S24. doi: 10.1186/1471-2105-9-S12-S24.

DOI:10.1186/1471-2105-9-S12-S24
PMID:19091024
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2638164/
Abstract

BACKGROUND

On-line biodiversity information databases are growing quickly and being integrated into general bioinformatics systems due to the advances of fast gene sequencing technologies and the Internet. These can reduce the cost and effort of performing biodiversity surveys and genetic searches, which allows scientists to spend more time researching and less time collecting and maintaining data. This will cause an increased rate of knowledge build-up and improve conservations. The biodiversity databases in Korea have been scattered among several institutes and local natural history museums with incompatible data types. Therefore, a comprehensive database and a nation wide web portal for biodiversity information is necessary in order to integrate diverse information resources, including molecular and genomic databases.

RESULTS

The Korean Natural History Research Information System (NARIS) was built and serviced as the central biodiversity information system to collect and integrate the biodiversity data of various institutes and natural history museums in Korea. This database aims to be an integrated resource that contains additional biological information, such as genome sequences and molecular level diversity. Currently, twelve institutes and museums in Korea are integrated by the DiGIR (Distributed Generic Information Retrieval) protocol, with Darwin Core2.0 format as its metadata standard for data exchange. Data quality control and statistical analysis functions have been implemented. In particular, integrating molecular and genetic information from the National Center for Biotechnology Information (NCBI) databases with NARIS was recently accomplished. NARIS can also be extended to accommodate other institutes abroad, and the whole system can be exported to establish local biodiversity management servers.

CONCLUSION

A Korean data portal, NARIS, has been developed to efficiently manage and utilize biodiversity data, which includes genetic resources. NARIS aims to be integral in maximizing bio-resource utilization for conservation, management, research, education, industrial applications, and integration with other bioinformation data resources. It can be found at http://www.naris.go.kr.

摘要

背景

由于快速基因测序技术和互联网的发展,在线生物多样性信息数据库正在迅速增长,并被整合到通用生物信息学系统中。这些数据库可以降低进行生物多样性调查和基因搜索的成本和工作量,使科学家能够将更多时间用于研究,而减少收集和维护数据的时间。这将加快知识积累速度并改善保护工作。韩国的生物多样性数据库分散在几个机构和地方自然历史博物馆中,数据类型不兼容。因此,有必要建立一个综合数据库和一个全国性的生物多样性信息网络门户,以整合包括分子和基因组数据库在内的各种信息资源。

结果

韩国自然历史研究信息系统(NARIS)已建成并作为中央生物多样性信息系统投入使用,用于收集和整合韩国各机构和自然历史博物馆的生物多样性数据。该数据库旨在成为一个包含额外生物信息(如基因组序列和分子水平多样性)的综合资源。目前,韩国的12个机构和博物馆通过DiGIR(分布式通用信息检索)协议进行整合,以达尔文核心2.0格式作为数据交换的元数据标准。已实现数据质量控制和统计分析功能。特别是,最近完成了将美国国立生物技术信息中心(NCBI)数据库中的分子和遗传信息与NARIS整合。NARIS还可以扩展以容纳国外的其他机构,并且整个系统可以导出以建立本地生物多样性管理服务器。

结论

已开发出韩国数据门户NARIS,以有效管理和利用包括遗传资源在内的生物多样性数据。NARIS旨在在最大限度地利用生物资源以进行保护、管理、研究、教育、工业应用以及与其他生物信息数据资源整合方面发挥不可或缺的作用。可通过http://www.naris.go.kr访问该网站。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5095/2638164/5f180ce46a0e/1471-2105-9-S12-S24-7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5095/2638164/3324e55cbab6/1471-2105-9-S12-S24-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5095/2638164/e571a00bd351/1471-2105-9-S12-S24-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5095/2638164/1830bc0d60c0/1471-2105-9-S12-S24-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5095/2638164/eec154a141c4/1471-2105-9-S12-S24-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5095/2638164/8c8af8327913/1471-2105-9-S12-S24-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5095/2638164/d41a91d8b431/1471-2105-9-S12-S24-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5095/2638164/5f180ce46a0e/1471-2105-9-S12-S24-7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5095/2638164/3324e55cbab6/1471-2105-9-S12-S24-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5095/2638164/e571a00bd351/1471-2105-9-S12-S24-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5095/2638164/1830bc0d60c0/1471-2105-9-S12-S24-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5095/2638164/eec154a141c4/1471-2105-9-S12-S24-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5095/2638164/8c8af8327913/1471-2105-9-S12-S24-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5095/2638164/d41a91d8b431/1471-2105-9-S12-S24-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5095/2638164/5f180ce46a0e/1471-2105-9-S12-S24-7.jpg

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