Cases Ildefonso, Pisano David G, Andres Eduardo, Carro Angel, Fernández José M, Gómez-López Gonzalo, Rodriguez Jose M, Vera Jaime F, Valencia Alfonso, Rojas Ana M
SCOMPBio Group, Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
Nucleic Acids Res. 2007 Jul;35(Web Server issue):W16-20. doi: 10.1093/nar/gkm280. Epub 2007 May 5.
There is a huge quantity of information generated in Life Sciences, and it is dispersed in many databases and repositories. Despite the broad availability of the information, there is a great demand for methods that are able to look for, gather and display distributed data in a standardized and friendly way. CARGO (Cancer And Related Genes Online) is a configurable biological web portal designed as a tool to facilitate, integrate and visualize results from Internet resources, independently of their native format or access method. Through the use of small agents, called widgets, supported by a Rich Internet Application (RIA) paradigm based on AJAX, CARGO provides pieces of minimal, relevant and descriptive biological information. The tool is designed to be used by experimental biologists with no training in bioinformatics. In the current state, the system presents a list of human cancer genes. Available at http://cargo.bioinfo.cnio.es.
生命科学领域产生了海量信息,这些信息分散在众多数据库和资源库中。尽管信息广泛可得,但人们迫切需要能够以标准化且友好的方式查找、收集和展示分布式数据的方法。CARGO(癌症及相关基因在线)是一个可配置的生物网络门户,设计用作一种工具,以促进、整合和可视化来自互联网资源的结果,而不考虑其原生格式或访问方法。通过使用由基于AJAX的富互联网应用(RIA)范式支持的称为小部件的小型代理程序,CARGO提供最小化、相关且具有描述性的生物信息片段。该工具旨在供未接受过生物信息学培训的实验生物学家使用。在当前状态下,该系统呈现了一份人类癌症基因列表。可在http://cargo.bioinfo.cnio.es获取。