Gumaste Vivek, Baum Joel
Department of Medicine, Mount Sinai Services at Elmhurst, Elmhurst General Hospital, Elmhurst, N.Y., USA.
Digestion. 2008;78(4):173-9. doi: 10.1159/000185690. Epub 2008 Dec 18.
Gastroparesis is a chronic disorder of gastric motility that is characterized by delayed emptying of either solids or liquids from the stomach in the absence of any mechanical obstruction. Nausea, vomiting, early satiety and bloating are some of the manifestations of gastroparesis. Idiopathic, diabetes mellitus and postsurgical states account for the majority of cases. Gastroparesis is a difficult condition to treat. Prokinetic drugs like metoclopramide and erythromycin form the mainstay of therapy but are less than ideal. Some patients may benefit from endoscopic botolinium toxin injection. Gastric electrical stimulation, though promising, is not ready for prime time yet.
胃轻瘫是一种慢性胃动力障碍性疾病，其特征是在没有任何机械性梗阻的情况下，胃内固体或液体排空延迟。恶心、呕吐、早饱感和腹胀是胃轻瘫的一些表现。特发性、糖尿病和术后状态占大多数病例。胃轻瘫是一种难以治疗的疾病。促动力药物如甲氧氯普胺和红霉素是主要的治疗药物，但并不理想。一些患者可能受益于内镜下肉毒杆菌毒素注射。胃电刺激虽然前景广阔，但尚未准备好广泛应用。
