Wiersema J R, van der Meere J J, Roeyers H
Department of Experimental-Clinical and Health Psychology, Ghent University, Ghent, Belgium.
J Neural Transm (Vienna). 2009 Mar;116(3):371-9. doi: 10.1007/s00702-008-0165-x. Epub 2008 Dec 18.
The purpose of the current study was to evaluate whether error monitoring difficulties persist in adults with attention deficit hyperactivity disorder (ADHD) using the event-related potential (ERP) methodology. Adults with ADHD and age-matched healthy controls executed a visual Go/No-Go task with 25% No-Go trials. Performance and ERP correlates of error monitoring were compared between groups. At the performance level no difference was noted between groups. However, exploring the error-related potentials revealed that the error-related negativity (ERN) was the same for both groups, but that adults with ADHD showed a smaller error positivity (Pe). Based on these findings, we conclude that adults with ADHD are normal in early automatic error detection, but are deviant in later conscious evaluation of the error. The findings add to the increasing evidence supporting disturbances in error monitoring in ADHD and show that these problems may persist in adulthood ADHD.
本研究的目的是使用事件相关电位（ERP）方法评估注意缺陷多动障碍（ADHD）成人患者是否存在错误监测困难。患有ADHD的成人和年龄匹配的健康对照者执行了一项视觉Go/No-Go任务，其中25%为No-Go试验。比较了两组之间错误监测的表现和ERP相关性。在表现水平上，两组之间没有差异。然而，对错误相关电位的探索发现，两组的错误相关负波（ERN）相同，但患有ADHD的成人表现出较小的错误正波（Pe）。基于这些发现，我们得出结论，患有ADHD的成人在早期自动错误检测方面是正常的，但在后期对错误的有意识评估方面存在偏差。这些发现进一步证明了支持ADHD中错误监测存在障碍的证据越来越多，并表明这些问题可能在成人ADHD中持续存在。
