Boer Olga D, Wiker Thea, Bukhari Shervin H, Kjelkenes Rikka, Timpe Clara M F, Voldsbekk Irene, Skaug Knut, Boen Rune, Karl Valerie, Moberget Torgeir, Westlye Lars T, Franken Ingmar H A, El Marroun Hanan, Huster Rene J, Tamnes Christian K
Department of Psychology, Education and Child Studies, Erasmus School of Social and Behavioral Science, Erasmus University Rotterdam, Rotterdam 3000 DR, Netherlands; Department of Child and Adolescent Psychiatry, University Medical Center Rotterdam, Erasmus MC, Sophia Children's Hospital, Rotterdam 3000 CB, Netherlands; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.
PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway; Center for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Division of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway.
Dev Cogn Neurosci. 2025 Jan;71:101500. doi: 10.1016/j.dcn.2024.101500. Epub 2024 Dec 24.
Detecting errors and adapting behavior accordingly constitutes an integral aspect of cognition. Previous studies have linked neural correlates of error processing (e.g., error-related negativity (ERN) and error-related positivity (Pe)) to task performance and broader behavioral constructs, but few studies examined how these associations manifest in adolescence. In this study, we examined neural error processing markers and their behavioral associations in an adolescent/emerging adult sample (N = 143, M = 18.0 years, range 11-25 years), employing a stop-signal task. Linear regressions were conducted using bootstrap resampling to explore associations between ERN/Pe peak amplitudes and latencies, stop accuracy, stop-signal reaction time (SSRT), and post-error slowing, as well as self-reported substance-related risks and problems and externalizing problems. After adjusting for age and sex, smaller frontocentral Pe amplitude and later Pe latency were associated with longer SSRT, and later Pe latency was associated with lower stop accuracy. This might indicate that the Pe, which is thought to reflect conscious error processing, reflects task performance on a response inhibition task better than the ERN, which reflects subconscious error processing. After correcting for multiple testing, there were no associations between ERN/Pe parameters and substance-related or externalizing problems, and no age interactions for these associations were detected.
检测错误并相应地调整行为是认知的一个重要方面。先前的研究已将错误处理的神经关联（例如，错误相关负波（ERN）和错误相关正波（Pe））与任务表现及更广泛的行为结构联系起来，但很少有研究考察这些关联在青少年时期是如何表现的。在本研究中，我们在一个青少年/新兴成年人样本（N = 143，M = 18.0岁，年龄范围11 - 25岁）中，采用停止信号任务，研究了神经错误处理标记及其行为关联。使用自抽样法进行线性回归，以探究ERN/Pe峰值幅度和潜伏期、停止准确性、停止信号反应时（SSRT）以及错误后反应减慢之间的关联，以及自我报告的与物质相关的风险和问题与外化问题之间的关联。在对年龄和性别进行校正后，额中央区较小的Pe幅度和较晚的Pe潜伏期与较长的SSRT相关，较晚的Pe潜伏期与较低的停止准确性相关。这可能表明，被认为反映有意识错误处理的Pe，在反应抑制任务中比反映潜意识错误处理的ERN能更好地反映任务表现。在对多重检验进行校正后，ERN/Pe参数与物质相关或外化问题之间没有关联，并且未检测到这些关联的年龄交互作用。
