Adeline Vilembwa L, Dimba Elizabeth A O, Wakoli Kevin A, Njiru Anthony K, Awange David O, Onyango John F, Chindia Mark L
Dental Unit, Kenyatta National Hospital, Nairobi, Kenya.
J Craniofac Surg. 2008 Nov;19(6):1589-93. doi: 10.1097/SCS.0b013e31818c0504.
This study describes the clinical and pathologic features of ameloblastomas seen in the 2 main craniofacial treatment centers in Kenya in the 10-year period between January 1995 and December 2005. A total of 184 patient records were analyzed for this study. Eighty-two (44.6%) of the patients were male, and 102 (55.4%) were female with an overall age range of 10 to 80 years (mean, 30.2 years; SD, 14.1 years). There was no significant difference in gender presentation of ameloblastomas, although females presented at a slightly older age. The mean age for males was 29.9 years, and for females, it was 30.5 years. Patients generally tended to seek medical advice late, with the mean duration at first presentation of 46.3 months for males and 44.4 months for females. Most of the ameloblastomas (n = 172; 93.5%) were located in the mandible, 11 (6.0%) were in the maxilla, and 1 (0.5%) was in the soft tissues. Presenting symptoms included swelling (n = 182; 98.9%), pain (n = 64; 36.0%), mobile teeth/history of extraction (n = 104; 57.5%), purulent discharge (n = 39; 21.7%) and paresthesia (n = 10; 5.6%). The posterior mandible was the most commonly affected site, whereas maxillary ameloblastomas tended to occur in anterior sites. One hundred fifty-three ameloblastomas (83.2%) were of the solid/multicystic subtype; 8 (5.3%) were unicystic; 1 (0.5%) was of extraosseous origin; 1 (0.5%) was desmoplastic; 9 (6.0%) were malignant, and 12 of the records had no histopathologic pattern specified.
本研究描述了1995年1月至2005年12月这10年间在肯尼亚两个主要颅面治疗中心所见到的成釉细胞瘤的临床和病理特征。本研究共分析了184份患者记录。其中82名（44.6%）患者为男性，102名（55.4%）为女性，总体年龄范围为10至80岁（平均30.2岁；标准差14.1岁）。成釉细胞瘤的性别表现无显著差异，不过女性就诊时年龄稍大。男性的平均年龄为29.9岁，女性为30.5岁。患者通常就医较晚，男性首次就诊时的平均病程为46.3个月，女性为44.4个月。大多数成釉细胞瘤（n = 172；93.5%）位于下颌骨，11例（6.0%）在上颌骨，1例（0.5%）位于软组织。主要症状包括肿胀（n = 182；98.9%）、疼痛（n = 64；36.0%）、牙齿松动/拔牙史（n = 104；57.5%）、脓性分泌物（n = 39；21.7%）和感觉异常（n = 10；5.6%）。下颌骨后部是最常受累部位，而上颌成釉细胞瘤往往发生在前部。153例成釉细胞瘤（83.2%）为实性/多囊性亚型；8例（5.3%）为单囊性；1例（0.5%）为骨外起源；1例（0.5%）为促结缔组织增生性；9例（6.0%）为恶性，12份记录未明确组织病理学类型。
