Filizzola Andressa-Incerte, Bartholomeu-dos-Santos Teresa-Cristina-Ribeiro, Pires Fábio-Ramôa
Oral Pathology, School of Dentistry, State University of Rio de Janeiro, Av. 28 de setembro, 157 - Vila Isabel, CEP: 20551-030 - Rio de Janeiro/RJ, Brazil,
Med Oral Patol Oral Cir Bucal. 2014 Nov 1;19(6):e556-61. doi: 10.4317/medoral.19802.
Ameloblastomas are odontogenic tumors that can present some distinct clinicopathological profiles when comparing different populations and studies.
The aim of the present study was to analyze the clinicopathological features from a series of ameloblastomas diagnosed in a single Oral Pathology service in Brazil in an 8-year period.
The files were revised and all cases diagnosed as ameloblastomas in the period were retrieved. All hematoxylin and eosin stained histological slides were reviewed and all clinical and radiological information were obtained through a review of the laboratory forms. Data were descriptively analyzed and a comparison was performed with the different ameloblastomas subtypes.
Seventy ameloblastomas composed the final sample, including 57 (81%) solid/multicystic, 9 (13%) unicystic, 2 (3%) desmoplastic and 2 (3%) peripheral ameloblastomas. Mean age of the affected patients was in the forth decade of life and there was a slight male predominance. Most tumors presented as multilocular radiolucencies, were located in the posterior mandible and showed the follicular and plexiform histological patterns. There was no difference on the mean age of the patients affected by solid and unicystic ameloblastomas.
The present results showed that the clinicopathological features of the ameloblastomas included in this Brazilian sample were similar to the features described in most other worldwide populations.
成釉细胞瘤是牙源性肿瘤,在比较不同人群和研究时可能呈现出一些不同的临床病理特征。
本研究的目的是分析在巴西一家口腔病理科8年间诊断的一系列成釉细胞瘤的临床病理特征。
查阅档案,检索该时期内所有诊断为成釉细胞瘤的病例。复查所有苏木精和伊红染色的组织学切片,并通过查阅实验室表格获取所有临床和放射学信息。对数据进行描述性分析,并与不同亚型的成釉细胞瘤进行比较。
最终样本包括70例成釉细胞瘤,其中实性/多囊性57例(81%)、单囊性9例(13%)、促结缔组织增生性2例(3%)、外周性2例(3%)。受影响患者的平均年龄在四十岁左右,男性略占优势。大多数肿瘤表现为多房性透射区,位于下颌骨后部,呈现滤泡状和丛状组织学模式。实性和单囊性成釉细胞瘤患者的平均年龄没有差异。
目前的结果表明,这个巴西样本中的成釉细胞瘤的临床病理特征与世界上大多数其他人群中描述的特征相似。