Sereda Danya, Sauthier Philippe, Hadjeres Rachid, Funaro Deana
Service de Dermatologie, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
J Low Genit Tract Dis. 2009 Jan;13(1):46-50. doi: 10.1097/LGT.0b013e318180436f.
Aggressive angiomyxoma is a variant of myxoid neoplasms of the female pelvic soft parts. The term "aggressive" refers to the tumor's locally infiltrative and recurrent nature because distant metastases are rare.
A 25-year-old woman presented with a 9-month history of an asymptomatic, polypoid mass arising from the right anterior labium minus. Histopathological and radiological examinations were consistent with a diagnosis of aggressive angiomyxoma. The patient was treated with a GnRH agonist followed by surgical excision.
We highlight the novel use of a GnRH agonist as a neoadjuvant to surgery in aggressive angiomyxoma to shrink the tumor preoperatively and decrease surgical morbidity.
侵袭性血管黏液瘤是女性盆腔软组织黏液样肿瘤的一种变体。“侵袭性”一词是指该肿瘤具有局部浸润和复发的特性，因为远处转移很少见。
一名25岁女性，有一个起源于右小阴唇前部的无症状息肉样肿物，病程9个月。组织病理学和放射学检查结果与侵袭性血管黏液瘤的诊断相符。该患者先接受促性腺激素释放激素（GnRH）激动剂治疗，随后进行手术切除。
我们强调了GnRH激动剂作为侵袭性血管黏液瘤手术新辅助药物的新用途，其可在术前缩小肿瘤并降低手术并发症发生率。
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