Whittaker P J, Sopwith W, Quigley C, Gillespie I, Willshaw G A, Lycett C, Surman-Lee S, Baxter D, Adak G K, Syed Q
Health Protection Agency, North West, Liverpool.
Epidemiol Infect. 2009 Mar;137(3):375-82. doi: 10.1017/S0950268808001702. Epub 2009 Feb 9.
A national outbreak of verotoxin-producing Escherichia coli O157 infection affected five English regions and Wales. Twelve cases were associated with lemon-and-coriander chicken wrap from a single supermarket chain consumed over a 5-day period. An outbreak investigation aimed to identify the source of infection. Descriptive epidemiology and phenotypic and genotypic tests on human isolates indicated a point-source outbreak; a case-control study showed a very strong association between consumption of lemon-and-coriander chicken wrap from the single supermarket chain and being a case (OR 46.40, 95% CI 5.39-infinity, P=0.0002). Testing of raw ingredients, products and faecal samples from staff in the food production unit did not yield any positive results. The outbreak was probably caused by one contaminated batch of an ingredient in the chicken wrap. Even when current best practice is in place, ready-to-eat foods can still be a risk for widespread infection.
一场由产志贺毒素大肠杆菌O157引发的全国性感染疫情波及了英格兰的五个地区和威尔士。12例病例与一家连锁超市在5天内售出的柠檬香菜鸡肉卷有关。一次疫情调查旨在确定感染源。对人类分离株进行的描述性流行病学以及表型和基因型检测表明这是一次点源暴发；一项病例对照研究显示，食用该连锁超市的柠檬香菜鸡肉卷与发病之间存在非常强的关联（比值比46.40，95%置信区间5.39至无穷大，P = 0.0002）。对食品生产单位的原材料、产品和工作人员粪便样本进行检测，未得到任何阳性结果。此次疫情可能是由鸡肉卷中的一批受污染食材导致的。即便当前已落实最佳做法，即食食品仍可能存在引发广泛感染的风险。
