Kanoh Toshiyuki, Nakano Yoshiaki, Inatome Junichi, Sakamoto Tetsuki, Kira Toshihiko, Miyazaki Susumu, Danno Katsuki, Kimura Yutaka, Iwazawa Takashi, Ohnishi Tadashi, Tono Takeshi, Yano Hiroshi, Monden Takushi, Imaoka Shingi
Dept. of Surgery, NTT West Osaka Hospital.
Gan To Kagaku Ryoho. 2008 Nov;35(12):2231-3.
Orbital metastasis from breast cancer is relatively rare. We report a case of successfully treated orbital metastasis from breast cancer by radiation therapy. This 50-year-old female patient underwent a mastectomy (Bt+Ax) of her left breast in October 2000. The diagnosis was invasive lobular carcinoma, Stage IIB (T2N1M0). Retroperitoneal and bladder metastases were found five years after the operation, and chemohormonal therapy was done. Right orbital swelling appeared 8 months after chemohormonal therapy, and orbital metastasis from breast cancer was diagnosed by MRI. Radiation therapy (a total 30 Gy) was administrated, and the swelling disappeared. An MRI was performed 16 months after radiation therapy and did not detect any metastases. A complete response (CR) was achieved. No sign of recurrence was found, and a sufficient local control has remained for 2 years after radiation therapy.
乳腺癌的眼眶转移相对少见。我们报告一例通过放射治疗成功治愈的乳腺癌眼眶转移病例。该50岁女性患者于2000年10月接受了左乳乳房切除术（乳房切除+腋窝清扫）。诊断为浸润性小叶癌，IIB期（T2N1M0）。术后5年发现腹膜后和膀胱转移，遂进行了化疗和激素治疗。化疗和激素治疗8个月后出现右侧眼眶肿胀，通过磁共振成像（MRI）诊断为乳腺癌眼眶转移。给予放射治疗（总计30 Gy），肿胀消失。放射治疗16个月后进行MRI检查，未发现任何转移灶。达到了完全缓解（CR）。未发现复发迹象，放射治疗后2年一直保持着充分的局部控制。
