Osajima Yuko, Sawabe Motoji, Hashimoto Ryo, Tsutsumi Hisashi, Arai Tomio, Ohta Masatsugu, Miyakoshi Shigesaburo
Division of Hematology, Tokyo Metropolitan Geriatric Hospital, Japan.
Rinsho Ketsueki. 2008 Dec;49(12):1599-603.
To investigate the actual situation of multiple cancers including hematological malignancies, 266 autopsy cases with one or more hematological malignancies were compiled from autopsy case files between January 1995 and October 2006 in our hospital. The median age at death was 75 years (range 48 to 102 yr). Of 266 cases, 72 (27.1%) had multiple cancers. Of these 72 cases, 62 cases were complicated with non-hematological malignancy, and 10 cases showed duplication of other hematological malignancies. Prostate and colon cancers were frequent as complicating cancers. Seventeen of 256 cases without duplication of other hematological malignancies demonstrated 3 or 4 cancers (6.6%). Of 10 cases showing duplication of other hematological malignancies, 9 cases had NHL. The rate of multiple cancers in elderly patients with hematological malignancy was higher than that of non-hematological cancers.
为了调查包括血液系统恶性肿瘤在内的多种癌症的实际情况,我们从我院1995年1月至2006年10月的尸检病例档案中整理出266例患有一种或多种血液系统恶性肿瘤的尸检病例。死亡时的中位年龄为75岁(范围48至102岁)。在266例病例中,72例(27.1%)患有多种癌症。在这72例病例中,62例合并非血液系统恶性肿瘤,10例表现为其他血液系统恶性肿瘤的重复。前列腺癌和结肠癌是常见的合并癌症。在256例无其他血液系统恶性肿瘤重复的病例中,17例显示有3种或4种癌症(6.6%)。在10例表现为其他血液系统恶性肿瘤重复的病例中,9例患有非霍奇金淋巴瘤。老年血液系统恶性肿瘤患者的多种癌症发生率高于非血液系统癌症患者。