Timofeeva N M, Egorova V V, Nikitina A A, Dmitrieva J V
I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia. nmtimof@ pavlov.infan.ru
Bull Exp Biol Med. 2008 Jun;145(6):676-9. doi: 10.1007/s10517-008-0179-2.
Early and late separation of rat pups from lactating females and combined effects of the terms of separation and low-protein diet are essential for the formation of enzymes (maltase, alkaline phosphatase, aminopeptidase M, and glycyl-L-leucine dipeptidase) in the large and small intestine, liver and kidneys of adult animals. Similarities and differences in the enzyme reactions to early and late weaning and to a combination of untimely weaning and low-protein diet were detected.
将幼鼠早期和晚期与哺乳母鼠分离,以及分离条件和低蛋白饮食的联合作用,对于成年动物的大肠、小肠、肝脏和肾脏中酶(麦芽糖酶、碱性磷酸酶、氨肽酶M和甘氨酰-L-亮氨酸二肽酶)的形成至关重要。检测到了酶对早期和晚期断奶以及对过早断奶和低蛋白饮食组合的反应中的异同。