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口腔癌:危险因素、预防与诊断

Oral cancer: risk factors, prevention and diagnostic.

作者信息

Khalili J

机构信息

Department of Therapeutic Stomatology, National Medical Academy of Postgraduate Education, 01004 Kiev, Ukraine.

出版信息

Exp Oncol. 2008 Dec;30(4):259-64.

Abstract

Although oral cancer is rare and attracts little attention, it ranks 12th among all cancers and constitutes the most life threatening of all dental conditions. The aetiology of oral cancer is multi-factorial and like other types of cancer, the key to decreasing the suffering of patients and increasing their survival rate is early detection. The global increase in frequency and mortality of oral cancer has intensified current research efforts in the field of prevention and early detection of this disease. Therefore, scientists have been searching for alternative approaches to biopsy. A number of molecular-based diagnostic markers have been used to detect the presence of oral cancer with varying degrees of sensitivity and specificity. In this paper, incidence, mortality, risk factors, prevention, and diagnostic of oral cancer have been reviewed.

摘要

尽管口腔癌较为罕见且鲜受关注,但在所有癌症中它位列第12位,是所有牙科疾病中对生命威胁最大的。口腔癌的病因是多因素的,与其他类型的癌症一样,减少患者痛苦并提高其生存率的关键在于早期发现。全球口腔癌发病率和死亡率的上升强化了当前在该疾病预防和早期检测领域的研究工作。因此,科学家们一直在寻找活检的替代方法。一些基于分子的诊断标志物已被用于检测口腔癌的存在,其敏感性和特异性各不相同。本文对口腔癌的发病率、死亡率、危险因素、预防和诊断进行了综述。

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