Elieff D, Sundby S, Kennedy W, Hordinsky M
Department of Dermatology, University of Minnesota Hospitals, Minneapolis 55455.
Br J Dermatol. 1991 Aug;125(2):130-5. doi: 10.1111/j.1365-2133.1991.tb06059.x.
In this study the number and function of sweat glands on the dorsum of the hand and foot were evaluated using a silastic imprint method. Twenty patients, 11 females and nine males with either alopecia areata, alopecia totalis, or alopecia universalis were included in the study. Patients showed a significant decrease in activated sweat-gland number and function compared to matched controls (P less than 0.001). There was no significant relationship between the degree of sweat-gland dysfunction and extent of hair loss, concurrent illnesses, or treatment. These findings suggest that eccrine sweat-gland function is compromised in patients with alopecia areata.
在本研究中，采用硅橡胶印模法对手足背部汗腺的数量和功能进行了评估。本研究纳入了20例患者，其中11例女性，9例男性，患有斑秃、全秃或普秃。与匹配的对照组相比，患者激活的汗腺数量和功能显著降低（P小于0.001）。汗腺功能障碍程度与脱发程度、并发疾病或治疗之间无显著关系。这些发现表明，斑秃患者的小汗腺功能受损。
