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芬兰中年人群中肥胖、中心性肥胖和糖耐量异常的高患病率。

High prevalence of obesity, central obesity and abnormal glucose tolerance in the middle-aged Finnish population.

作者信息

Saaristo Timo E, Barengo Noël C, Korpi-Hyövälti Eeva, Oksa Heikki, Puolijoki Hannu, Saltevo Juha T, Vanhala Mauno, Sundvall Jouko, Saarikoski Liisa, Peltonen Markku, Tuomilehto Jaakko

机构信息

Finnish Diabetes Association, Tampere, Finland.

出版信息

BMC Public Health. 2008 Dec 29;8:423. doi: 10.1186/1471-2458-8-423.

Abstract

BACKGROUND

There is a worldwide increase in the prevalence of obesity and disturbances in glucose metabolism. The aim of this study was to assess the current prevalence of obesity, central obesity and abnormal glucose tolerance in Finnish population, and to investigate the associations between body mass index (BMI), waist circumference and abnormal glucose tolerance.

METHODS

A cross-sectional population-based survey was conducted in Finland during October 2004 and January 2005. A total of 4500 randomly selected individuals aged 45-74 years were invited to a health examination that included an oral glucose tolerance test. The participation rate was 62% in men and 67% in women.

RESULTS

The prevalence of obesity was 23.5% (95% Confidence Interval (CI) 21.1-25.9) in men, and 28.0% (95% CI 25.5-30.5) in women. The overall prevalence of abnormal glucose tolerance (including type 2 diabetes, impaired glucose tolerance, or impaired fasting glucose) was 42.0% (95% CI 39.2-44.8) in men and 33.4% (95% CI 30.9-36.0) in women. The prevalence of previously unknown, screen-detected type 2 diabetes was 9.3% (95% CI 7.7-11.0) in men and 7.3% (95% CI 5.9-8.7) in women. Central obesity was associated with abnormal glucose tolerance within each of the three BMI categories normal (< 25 kg/m2), overweight (25-29 kg/m2), and obese (>or= 30 kg/m2).

CONCLUSION

In a population-based random sample of Finnish population, prevalences of obesity, central obesity and abnormal glucose tolerance were found to be high. A remarkably high number of previously undetected cases of type 2 diabetes was detected. Waist circumference is a predictor of abnormal glucose tolerance in all categories of obesity.

摘要

背景

全球肥胖率及糖代谢紊乱情况呈上升趋势。本研究旨在评估芬兰人群中肥胖、中心性肥胖及糖耐异常的当前患病率,并探究体重指数(BMI)、腰围与糖耐异常之间的关联。

方法

2004年10月至2005年1月在芬兰开展了一项基于人群的横断面调查。共邀请4500名年龄在45 - 74岁的随机选取个体参加包含口服葡萄糖耐量试验的健康检查。男性参与率为62%,女性为67%。

结果

男性肥胖患病率为23.5%(95%置信区间(CI)21.1 - 25.9),女性为28.0%(95% CI 25.5 - 30.5)。男性糖耐异常(包括2型糖尿病、糖耐量受损或空腹血糖受损)总体患病率为42.0%(95% CI 39.2 - 44.8),女性为33.4%(95% CI 30.9 - 36.0)。既往未知、经筛查发现的2型糖尿病患病率男性为9.3%(95% CI 7.7 - 11.0),女性为7.3%(95% CI 5.9 - 8.7)。在BMI正常(<25 kg/m²)、超重(25 - 29 kg/m²)和肥胖(≥30 kg/m²)这三个类别中,中心性肥胖均与糖耐异常相关。

结论

在芬兰人群的基于人群的随机样本中,肥胖、中心性肥胖及糖耐异常的患病率较高。检测出大量既往未被发现的2型糖尿病病例。腰围是所有肥胖类别中糖耐异常的一个预测指标。

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