Ong Jason C, Shapiro Shauna L, Manber Rachel
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Explore (NY). 2009 Jan-Feb;5(1):30-6. doi: 10.1016/j.explore.2008.10.004.
A unique intervention combining mindfulness meditation with cognitive behavioral therapy for insomnia (CBT-I) has been shown to have acute benefits at posttreatment in an open label study. The aim of the present study was to examine the long-term effects of this integrated intervention on measures of sleep and sleep-related distress in an attempt to characterize the natural course of insomnia following this treatment and to identify predictors of poor long-term outcome. Analyses were conducted on 21 participants, who provided follow-up data at six and 12 months posttreatment. At each time point, participants completed one week of sleep and meditation diaries and questionnaires related to mindfulness, sleep, and sleep-related distress, including the Pre-Sleep Arousal Scale, the Glasgow Sleep Effort Scale, the Kentucky Inventory of Mindfulness Skills, and the Insomnia Episode Questionnaire. Analyses examining the pattern of change across time (baseline, end of treatment, six months, and 12 months) revealed that several sleep-related benefits were maintained during the 12-month follow-up period. Participants who reported at least one insomnia episode (>or=1 month) during the follow-up period had higher scores on the Pre-Sleep Arousal Scale (P < .05) and the Glasgow Sleep Effort Scale (P < .05) at end of treatment compared with those with no insomnia episodes. Correlations between mindfulness skills and insomnia symptoms revealed significant negative correlations (P < .05) between mindfulness skills and daytime sleepiness at each of the three time points but not with nocturnal symptoms of insomnia. These results suggest that most sleep-related benefits of an intervention combining CBT-I and mindfulness meditation were maintained during the 12-month follow-up period, with indications that higher presleep arousal and sleep effort at end of treatment constitute a risk for occurrence of insomnia during the 12 months following treatment.
在一项开放标签研究中,一种将正念冥想与失眠认知行为疗法(CBT-I)相结合的独特干预措施已被证明在治疗后具有即时益处。本研究的目的是检验这种综合干预措施对睡眠及睡眠相关困扰指标的长期影响,以试图描述该治疗后失眠的自然病程,并确定长期预后不良的预测因素。对21名参与者进行了分析,他们在治疗后6个月和12个月提供了随访数据。在每个时间点,参与者完成了一周的睡眠和冥想日记以及与正念、睡眠和睡眠相关困扰有关的问卷,包括睡前觉醒量表、格拉斯哥睡眠努力量表、肯塔基正念技能量表和失眠发作问卷。对跨时间(基线、治疗结束、6个月和12个月)变化模式的分析显示,在12个月的随访期内,几种与睡眠相关的益处得以维持。在随访期内报告至少一次失眠发作(≥1个月)的参与者,与无失眠发作的参与者相比,在治疗结束时的睡前觉醒量表(P<.05)和格拉斯哥睡眠努力量表(P<.05)上得分更高。正念技能与失眠症状之间的相关性显示,在三个时间点中的每一个时间点,正念技能与白天嗜睡之间均存在显著负相关(P<.05),但与失眠的夜间症状无关。这些结果表明,在12个月的随访期内,CBT-I与正念冥想相结合的干预措施的大多数与睡眠相关的益处得以维持,有迹象表明治疗结束时较高的睡前觉醒和睡眠努力是治疗后12个月内发生失眠的一个风险因素。