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通过短信应用程序提供正念干预失眠、疼痛和功能失调性进食:三项随机对照试验研究其有效性和中介机制。

Delivering Mindfulness-Based Interventions for Insomnia, Pain, and Dysfunctional Eating Through a Text Messaging App: Three Randomized Controlled Trials Investigating the Effectiveness and Mediating Mechanisms.

机构信息

Department of Psychology, The Chinese University of Hong Kong, Hong Kong, Hong Kong.

Clinical Psychological Services, New Life Psychiatric Rehabilitation Association, Hong Kong, Hong Kong.

出版信息

J Med Internet Res. 2022 May 3;24(5):e30073. doi: 10.2196/30073.

Abstract

BACKGROUND

Although text messaging has the potential to be the core intervention modality, it is often used as an adjunct only. To improve health and alleviate the distress related to insomnia, pain, and dysregulated eating of people living in urban areas, text messaging-based mindfulness-based interventions were designed and evaluated in 3 randomized controlled trials.

OBJECTIVE

This study investigated the effectiveness and mediating mechanisms of text messaging-based mindfulness-based interventions for people with distress related to insomnia, pain, or dysregulated eating.

METHODS

In these trials, 333, 235, and 351 participants were recruited online and randomized to intervention and wait-list control conditions for insomnia, pain, and dysregulated eating, respectively. Participants experienced 21 days of intervention through WhatsApp Messenger. Participants completed pre-, post-, 1-month follow-up, and 3-month follow-up self-report questionnaires online. The retention rates at postmeasurements were 83.2% (139/167), 77.1% (91/118), and 72.9% (129/177) for intervention groups of insomnia, pain, and dysregulated eating, respectively. Participants' queries were answered by a study technician. Primary outcomes included insomnia severity, presleep arousal, pain intensity, pain acceptance, and eating behaviors. Secondary outcomes included mindfulness, depression, anxiety, mental well-being, and functional impairments. Mindfulness, dysfunctional beliefs and attitudes about sleep, pain catastrophizing, and reactivity to food cues were hypothesized to mediate the relationship between the intervention and outcomes.

RESULTS

For all 3 studies, the intervention groups showed significant improvement on most outcomes at 1-month follow-up compared to their respective wait-list control groups; some primary outcomes (eg, insomnia, pain, dysregulated eating indicators) and secondary outcomes (eg, depression, anxiety symptoms) were sustained at 3-month follow-up. Medium-to-large effect sizes were found at postassessments in most outcomes in all studies. In the intervention for insomnia, mediation analyses showed that dysfunctional beliefs and attitudes about sleep mediated the effect of the intervention on all primary outcomes and most secondary outcomes at both 1-month and 3-month follow-ups, whereas mindfulness mediated the intervention effect on presleep arousal at 1-month and 3-month follow-ups. In the intervention for pain, pain catastrophizing mediated the effect of intervention on pain intensity and functioning at both 1-month and 3-month follow-ups, whereas mindfulness only mediated the effect of intervention on anxiety and depressive symptoms. In the intervention for dysregulated eating, power of food mediated the effect of intervention on both uncontrolled and emotional eating at both 1-month and 3-month follow-ups and mindfulness was found to mediate the effect on depressive symptoms at both 1-month and 3-month follow-ups.

CONCLUSIONS

These 3 studies converged and provided empirical evidence that mindfulness-based interventions delivered through text messaging are effective in improving distress related to sleep, pain, and dysregulated eating. Text messaging has the potential to be a core intervention modality to improve various common health outcomes for people living a fast-paced lifestyle.

TRIAL REGISTRATION

Clinical Research and Biostatistics Clinical Trials Registry CUHK_CCRB00559; https://tinyurl.com/24rkwarz.

摘要

背景

尽管短信在潜力上可以成为核心干预手段,但它通常仅作为辅助手段使用。为了改善城市居民的睡眠障碍、疼痛和饮食失调相关的健康状况并减轻他们的痛苦,我们设计并评估了 3 项基于短信的正念干预研究。

目的

本研究旨在调查基于短信的正念干预对睡眠障碍、疼痛和饮食失调相关困扰人群的有效性及其潜在的中介机制。

方法

在这 3 项试验中,分别通过在线招募了 333、235 和 351 名参与者,并将他们随机分配到干预组和等待名单对照组,以研究睡眠障碍、疼痛和饮食失调。参与者通过 WhatsApp 信使接受 21 天的干预。参与者在线完成了预测量、后测量、1 个月随访和 3 个月随访的自我报告问卷。睡眠障碍、疼痛和饮食失调的干预组在后期测量时的保留率分别为 83.2%(139/167)、77.1%(91/118)和 72.9%(129/177)。参与者的问题由一名研究技术员解答。主要结局指标包括睡眠障碍严重程度、睡前觉醒、疼痛强度、疼痛接受度和饮食行为。次要结局指标包括正念、抑郁、焦虑、心理幸福感和功能障碍。假设正念、对睡眠的不良信念和态度、疼痛灾难化和对食物线索的反应性将在干预和结局之间起到中介作用。

结果

对于所有 3 项研究,干预组在 1 个月随访时与各自的等待名单对照组相比,在大多数结局上均有显著改善;一些主要结局(如睡眠、疼痛、饮食失调指标)和次要结局(如抑郁、焦虑症状)在 3 个月随访时仍持续存在。在大多数结局中,在大多数研究的后测量中均发现了中到大的效应量。在睡眠障碍干预研究中,中介分析表明,对睡眠的不良信念和态度在 1 个月和 3 个月随访时,均中介了干预对所有主要结局和大多数次要结局的影响,而正念则在 1 个月和 3 个月随访时,中介了干预对睡前觉醒的影响。在疼痛干预研究中,疼痛灾难化在 1 个月和 3 个月随访时,中介了干预对疼痛强度和功能的影响,而正念仅在 1 个月和 3 个月随访时,中介了干预对抑郁和焦虑症状的影响。在饮食失调干预研究中,食物的力量在 1 个月和 3 个月随访时,均中介了干预对失控和情绪性进食的影响,而正念在 1 个月和 3 个月随访时,均中介了干预对抑郁症状的影响。

结论

这 3 项研究的结果一致,为通过短信提供的正念干预对睡眠、疼痛和饮食失调相关困扰的改善提供了实证证据。短信有可能成为改善快节奏生活方式人群各种常见健康结局的核心干预手段。

试验注册

临床试验和生物统计学临床试验注册处 CUHK_CCRB00559;https://tinyurl.com/24rkwarz。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2216/9115660/91bcb2dd8bec/jmir_v24i5e30073_fig1.jpg

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