非结核分枝杆菌血流和心脏感染，发生于无 HIV 感染的患者中。
Nontuberculous mycobacterial blood stream and cardiac infections in patients without HIV infection.
机构信息
Department of Infectious Diseases, Cleveland Clinic, Cleveland, OH 44195, USA.
出版信息
Diagn Microbiol Infect Dis. 2010 Jul;67(3):286-90. doi: 10.1016/j.diagmicrobio.2010.02.006. Epub 2010 May 11.
Abstract
Nontuberculous mycobacteria rarely cause bacteremia in HIV-negative patients. We describe 16 cases, including the first Mycobacterium neoaurum endocarditis. Nine cases were line related. Most patients were immunocompromised secondary to hematologic malignancy or other comorbid conditions. Amikacin had the most reliable in vitro activity. Combination therapy was frequently used. Mortality was 25%.
摘要
非结核分枝杆菌很少在 HIV 阴性患者中引起菌血症。我们描述了 16 例病例，包括首例 Mycobacterium neoaurum 心内膜炎。9 例与导管相关。大多数患者因血液系统恶性肿瘤或其他合并症而免疫功能低下。阿米卡星具有最可靠的体外活性。联合治疗经常使用。死亡率为 25%。
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