来自台湾金丝桃的色酮和色满酮糖苷及其抗幽门螺杆菌活性。
Chromone and chromanone glucosides from Hypericum sikokumontanum and their anti-Helicobacter pylori activities.
作者信息
Tanaka Naonobu, Kashiwada Yoshiki, Nakano Tatsuro, Shibata Hirofumi, Higuchi Tomihiko, Sekiya Michiko, Ikeshiro Yasumasa, Takaishi Yoshihisa
机构信息
Graduate School of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan.
出版信息
Phytochemistry. 2009 Jan;70(1):141-6. doi: 10.1016/j.phytochem.2008.11.006. Epub 2008 Dec 31.
Chromone glucosides, takanechromones A-C (1, 2 and 5) and chromanone glucosides, named takanechromanones A and B (3 and 4), were isolated from the methanolic extracts of Hypericumsikokumontanum together with 27 known compounds. Their structures were established based on spectroscopic evidence. The isolated compounds and some chromone derivatives were assayed for antimicrobial activity against Helicobacter pylori and cytotoxicity against human cancer cell lines.
从黄海棠的甲醇提取物中分离得到色酮糖苷、高野色酮A - C（1、2和5）以及色满酮糖苷，即高野色满酮A和B（3和4），同时还分离得到27种已知化合物。它们的结构通过光谱证据得以确定。对分离得到的化合物以及一些色酮衍生物进行了抗幽门螺杆菌的抗菌活性和对人癌细胞系的细胞毒性测定。
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