Lundy J Jason, Coons Stephen Joel, Wendel Christopher, Hornbrook Mark C, Herrinton Lisa, Grant Marcia, Krouse Robert S
College of Pharmacy, University of Arizona, P.O. Box 210202, Tucson, AZ, 85721-0202, USA.
Qual Life Res. 2009 Mar;18(2):157-61. doi: 10.1007/s11136-008-9432-4. Epub 2009 Jan 10.
The purpose of this analysis was to determine the unique contribution of household income to the variance explained in psychological well-being (PWB) among a sample of colorectal cancer (CRC) survivors.
This study is a secondary analysis of data collected as part of the Health-Related Quality of Life in Long-Term Colorectal Cancer Survivors Study, which included CRC survivors with (cases) and without (controls) ostomies. The dataset included socio-demographic, health status, and health-related quality of life (HRQOL) information. HRQOL was assessed with the modified City of Hope Quality of Life (mCOH-QOL)-Ostomy questionnaire and SF-36v2. To assess the relationship between income and PWB, a hierarchical linear regression model was constructed combining data from both cases and controls.
After accounting for the proportion of variance in PWB explained by the other independent variables in the model, the additional variance explained by income was significant (R (2) increased from 0.228 to 0.250; P = 0.006).
Although the study design does not allow causal inference, these results demonstrate a significant relationship between income and PWB in CRC survivors. The findings suggest that for non-randomized group comparisons of HRQOL, income should, at the very least, be included as a control variable in the analysis.
本分析的目的是确定家庭收入对一组结直肠癌(CRC)幸存者心理健康(PWB)所解释的方差的独特贡献。
本研究是对作为长期结直肠癌幸存者健康相关生活质量研究一部分收集的数据进行的二次分析,该研究纳入了有(病例组)和无(对照组)造口术的CRC幸存者。数据集包括社会人口统计学、健康状况和健康相关生活质量(HRQOL)信息。HRQOL通过改良的希望之城生活质量(mCOH-QOL)-造口术问卷和SF-36v2进行评估。为了评估收入与PWB之间的关系,构建了一个层次线性回归模型,将病例组和对照组的数据合并在一起。
在考虑模型中其他自变量所解释的PWB方差比例后,收入所解释的额外方差具有显著性(R(2)从0.228增加到0.250;P = 0.006)。
尽管研究设计不允许进行因果推断,但这些结果表明CRC幸存者的收入与PWB之间存在显著关系。研究结果表明,对于HRQOL的非随机组比较,在分析中至少应将收入作为一个控制变量纳入。