Allen Jennifer D, Mohllajee Anshu P, Shelton Rachel C, Othus Megan K D, Fontenot Holly B, Hanna Richard
Center for Community-Based Research, Dana-Farber Cancer Institute, Boston, MA, USA.
Prev Med. 2009 May;48(5):420-5. doi: 10.1016/j.ypmed.2008.12.005. Epub 2008 Dec 24.
Certain types of human papillomavirus (HPV) can cause cervical and other cancers. A vaccine that protects against HPV types responsible for 70% of cervical cancers is available to females ages 9-26.
To examine correlates of stage of vaccine adoption among women ages 18-22.
In 2007, female students (n=4774) at a New England University in the U.S. were invited to complete an on-line survey that assessed knowledge of HPV, perceived susceptibility, severity, vaccine benefits/barriers, social and subjective norms, and stage of vaccine adoption
1897 women (40%) responded; complete data were available for 1401. About half (53%) were planning to be vaccinated, 12% had received the vaccine, 15% were undecided, and 7% had decided against vaccination. HPV knowledge was low (mean 58%). In multivariate analyses, social norms was the strongest correlate of stage; each standard deviation increase in social norms score was associated with more than four times the odds of intending to be vaccinated within the next 30 days, compared with those who had decided against vaccination (OR=4.15; 95% CI 2.17-6.36).
Acceptance of the vaccine was high, although misconceptions about viral transmission, availability of treatment, and the role of Pap tests were common. Perceived norms were strongly associated with intentions. Interventions on college campuses should stress vaccination as a normative behavior, provide information about viral transmission, and stress the role of continued Pap screening.
某些类型的人乳头瘤病毒(HPV)可引发宫颈癌及其他癌症。一种可预防导致70%宫颈癌的HPV类型的疫苗可供9至26岁的女性使用。
研究18至22岁女性中疫苗接种阶段的相关因素。
2007年,邀请美国一所新英格兰大学的女学生(n = 4774)完成一项在线调查,该调查评估了HPV知识、感知易感性、严重性、疫苗益处/障碍、社会和主观规范以及疫苗接种阶段。
1897名女性(40%)做出回应;1401名有完整数据。约一半(53%)计划接种疫苗,12%已接种疫苗,15%未做决定,7%已决定不接种。HPV知识水平较低(平均58%)。在多变量分析中,社会规范是与接种阶段关联最强的因素;与已决定不接种疫苗的人相比,社会规范得分每增加一个标准差,在未来30天内打算接种疫苗的几率增加四倍多(比值比=4.15;95%置信区间2.17 - 6.36)。
尽管对病毒传播、治疗可用性和巴氏试验的作用存在常见误解,但疫苗的接受度较高。感知规范与接种意愿密切相关。大学校园的干预措施应强调接种疫苗是一种规范行为,提供有关病毒传播的信息,并强调持续进行巴氏筛查的作用。