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在悉生小鼠中，作为预防剂使用的布拉氏酵母菌的剂量和活力对艰难梭菌诱导死亡率的调节作用。

Modulation of Clostridium difficile induced mortality as a function of the dose and the viability of the Saccharomyces boulardii used as a preventative agent in gnotobiotic mice.

作者信息

Elmer G W, Corthier G

机构信息

Laboratoire d'écologie et de physiologie du systeme digestif, Centre de recherches de Jouy-en-Josas, France.

出版信息

Can J Microbiol. 1991 Apr;37(4):315-7. doi: 10.1139/m91-049.

DOI:10.1139/m91-049
PMID:1913342
Abstract

The ability of viable and nonviable Saccharomyces boulardii to protect gnotobiotic mice from Clostridium difficile induced mortality was tested. With the exception of irradiated S. boulardii, which retained some activity, only viable yeast protected the mice from lethality. The survival of C. difficile infected mice was dependent on the dose of the yeast provided in the drinking water.

摘要

测试了活的和灭活的布拉氏酵母菌保护悉生小鼠免受艰难梭菌诱导死亡的能力。除了保留一些活性的辐照布拉氏酵母菌外，只有活酵母能保护小鼠免于死亡。艰难梭菌感染小鼠的存活取决于饮用水中提供的酵母剂量。

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Modulation of Clostridium difficile induced mortality as a function of the dose and the viability of the Saccharomyces boulardii used as a preventative agent in gnotobiotic mice.在悉生小鼠中，作为预防剂使用的布拉氏酵母菌的剂量和活力对艰难梭菌诱导死亡率的调节作用。
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