分离的成牙本质细胞中的组织蛋白酶D活性。

Cathepsin D activity in isolated odontoblasts.

作者信息

Linde A, Persliden B

出版信息

Calcif Tissue Res. 1977 May 31;23(1):33-8. doi: 10.1007/BF02012763.

DOI:10.1007/BF02012763

PMID:19134

Abstract

The presence of an acid proteinase with a high activity has been demonstrated in isolated odontoblast-predentine material from dentinogenically active rat incisors. The enzyme was identified as cathepsin D (EC 3.4.23.5). The possible significance of the enzymatic degradation of proteoglycans and glycosaminoglycans in the course of the calcification process is discussed.

摘要

在源自牙本质生成活跃的大鼠切牙的分离成牙本质细胞-前期牙本质材料中，已证实存在一种具有高活性的酸性蛋白酶。该酶被鉴定为组织蛋白酶D（EC 3.4.23.5）。本文讨论了在钙化过程中蛋白聚糖和糖胺聚糖酶促降解的可能意义。