3-巯基丙酸介导的肽和蛋白质硫酯的合成。
3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters.
作者信息
Kang Jaskiranjit, Richardson Jonathan P, Macmillan Derek
机构信息
Department of Chemistry, University College London, 20 Gordon Street, London, UK.
出版信息
Chem Commun (Camb). 2009 Jan 28(4):407-9. doi: 10.1039/b815888f. Epub 2008 Nov 5.
Abstract
Peptides and proteins fragment sequence-specifically in the presence of 3-mercaptopropionic acid to afford thioesters which can be used in native chemical ligation reactions.
摘要
在3-巯基丙酸存在下，肽和蛋白质会发生序列特异性断裂，生成硫酯，这些硫酯可用于天然化学连接反应。
Zotero 插件