Cristiano E, Patrucco L, Rojas J I, Cáceres F, Carrá A, Correale J, Garcea O, Gold L, Tessler J, Kremenchutzky M
MS Section, Hospital Italiano, Buenos Aires, Argentina.
Eur J Neurol. 2009 Feb;16(2):183-7. doi: 10.1111/j.1468-1331.2008.02375.x. Epub 2008 Dec 9.
Scarce data exist about multiple sclerosis (MS) prevalence in South America. The objective of the study is to determine the prevalence of MS in a high populated area from Argentina (Greater Buenos Aires Metropolitan area) using the capture-recapture methodology.
Greater Buenos Aires is the generic denomination that refers to the megalopolis comprised by the autonomous city of Buenos Aires and the surrounding conurbation of the province of Buenos Aires. The study was carried out taking July 1996 as the prevalence month. We used capture-recapture method to estimate the prevalence of MS cross matching registries from four MS Centers.
A total of 803 registries were obtained from the four lists. Log-linear model for capture-recapture method was used to analyze the data. The population of the area based on the 1990 census was 12,594,974; the number of MS cases estimated amongst sources interactions were between 1833 and 2359; the prevalence estimated ranged from 14 to 19.8 cases per 100,000 inhabitants.
This is the first study to provide epidemiological data on the prevalence of MS in a large population in Argentina (Greater Buenos Aires Metropolitan area). Further epidemiological studies will clarify the true prevalence of MS in South America.
关于南美洲多发性硬化症（MS）患病率的数据稀少。本研究的目的是使用捕获-再捕获方法确定阿根廷一个人口密集地区（大布宜诺斯艾利斯都会区）的MS患病率。
大布宜诺斯艾利斯是一个通用名称，指的是由布宜诺斯艾利斯自治市和布宜诺斯艾利斯省周边的城市群组成的大都市。该研究以1996年7月作为患病率统计月份。我们使用捕获-再捕获方法，通过对四个MS中心的登记数据进行交叉匹配来估计MS的患病率。
从这四个列表中总共获得了803个登记数据。使用捕获-再捕获方法的对数线性模型对数据进行分析。根据1990年人口普查，该地区人口为12594974；在数据源交互中估计的MS病例数在1833至2359之间；估计的患病率为每10万居民14至19.8例。
这是第一项提供阿根廷一个大人口地区（大布宜诺斯艾利斯都会区）MS患病率流行病学数据的研究。进一步的流行病学研究将阐明南美洲MS的真实患病率。
