Met Office, Exeter, UK.
Respir Med. 2009 Apr;103(4):558-65. doi: 10.1016/j.rmed.2008.10.027. Epub 2009 Jan 10.
Hospital admissions for exacerbations of chronic obstructive pulmonary disease (COPD) impact considerably on disease evolution and healthcare provision. Building on previous studies, this study postulated that COPD patients could be stratified by risk of admission to determine which groups provide the greatest burden on resources, and how interventions should be targeted to prevent admissions.
COPD admissions during 1997-2003 in three Strategic Health Authorities in England were analysed (n=80,291). Patients admitted during winter (1 November-31 March) were stratified into three groups according to the number of admissions during the previous year: 0 (NIL), 1-2 (MOD) or >or=3 (FRQ). Winter weeks were classified as "average", "above average", "high", or "very high" risk, compared with the long-term mean.
The risk of admission during winter for FRQ and MOD patients was 40% and 12% respectively. NIL patients contributed to 70% of winter admissions, and 90% of the variation between "average" and "very high" weeks, versus 9% and 1% for MOD and FRQ.
Patients with no previous admissions have lower individual risk, but contribute to a high overall utilisation of health care resources and should be targeted to prevent admissions. Focusing upon high-risk patients (frequent attenders or more severe) may only reduce a small proportion of admissions, and therefore clinicians should ensure that all COPD patients receive appropriate therapy to reduce risk of exacerbations.
慢性阻塞性肺疾病(COPD)恶化导致的住院治疗对疾病进展和医疗保健服务有重大影响。本研究在先前研究的基础上假设,可以根据住院风险对 COPD 患者进行分层,以确定哪些群体对资源造成的负担最大,以及如何针对这些群体进行干预以预防住院。
分析了英格兰三个战略卫生局在 1997 年至 2003 年期间 COPD 的住院情况(n=80,291)。将冬季(11 月 1 日至 3 月 31 日)住院的患者根据前一年的住院次数分为三组:0 次(NIL)、1-2 次(MOD)或≥3 次(FRQ)。与长期平均值相比,冬季周被分为“平均”、“高于平均”、“高”或“非常高”风险。
FRQ 和 MOD 患者冬季住院的风险分别为 40%和 12%。NIL 患者占冬季住院患者的 70%,占“平均”和“非常高”周之间的 90%,而 MOD 和 FRQ 患者仅占 9%和 1%。
没有既往住院史的患者个体风险较低,但对卫生保健资源的总体利用贡献较高,应针对这些患者进行预防住院治疗。关注高风险患者(频繁就诊者或更严重者)可能仅能减少一小部分住院,因此临床医生应确保所有 COPD 患者都接受适当的治疗以降低恶化风险。