Halpin Dmg, Holmes S, Calvert J, McInerney D
SW Respiratory Associate Strategic Clinical Network, Bristol, UK.
Chron Respir Dis. 2016 Nov;13(4):337-343. doi: 10.1177/1479972316643011. Epub 2016 Jul 8.
Despite increased interest and awareness of chronic obstructive pulmonary disease (COPD), nearly half of the people with COPD remain undiagnosed. Inviting people at risk for screening is unlikely to be effective as many will not attend. Co-morbidities are common in people with COPD but COPD is also a comorbidity of other long-term conditions and people with these conditions are under regular review in primary care clinics. This study aimed to develop a pilot programme to case find people with COPD among patients attending other long-term clinics in primary care. Twenty-three general practices were recruited to participate in South West England. All current or ex-smokers aged ≥35 attending a long-term condition clinic who were not known to have COPD were asked to complete a questionnaire designed to help identify people with COPD and to perform microspirometry. Practices were asked to collect data on up to 100 patients. One thousand three hundred and thirty-three patients were assessed. Four hundred and ten people (31%) were current smokers. Six hundred and thirteen (46%) had high questionnaire scores and 287 (22%) of these also had a forced expiratory volume in 1 second (FEV) below the lower limit of normal (LLN). The mean FEV in these patients was 59.0% of predicted (range 22-79.0%). Two hundred and twenty-four had an FEV between 50% and 80% of predicted, 50 had an FEV between 30% and 50% of predicted. One hundred and sixteen (40%) of the people with an FEV below the LLN were still smoking and 55 accepted referral to cessation services. A total of 56% of the other smokers assessed but not thought to have COPD also accepted referral. Assessing symptoms and performing microspirometry in people attending long-term condition clinics in primary care is feasible and has a high yield of identifying people likely to have previously undiagnosed COPD.
尽管人们对慢性阻塞性肺疾病(COPD)的关注度和认识有所提高,但仍有近一半的COPD患者未被诊断出来。邀请有风险的人群进行筛查不太可能有效,因为许多人不会前来。合并症在COPD患者中很常见,但COPD也是其他长期疾病的合并症,患有这些疾病的人在基层医疗诊所会接受定期检查。本研究旨在制定一个试点项目,以便在基层医疗中其他长期诊所就诊的患者中发现COPD患者。招募了23家全科诊所参与英格兰西南部的研究。所有年龄≥35岁、在长期疾病诊所就诊且不知患有COPD的现吸烟者或既往吸烟者,均被要求填写一份旨在帮助识别COPD患者的问卷,并进行微型肺活量测定。各诊所被要求收集多达100名患者的数据。共评估了1333名患者。410人(31%)为现吸烟者。613人(46%)问卷得分较高,其中287人(22%)的1秒用力呼气容积(FEV)低于正常下限(LLN)。这些患者的平均FEV为预测值的59.0%(范围为22 - 79.0%)。224人的FEV在预测值的50%至80%之间,50人的FEV在预测值的30%至50%之间。FEV低于LLN的患者中有116人(40%)仍在吸烟,55人接受了戒烟服务转诊。在接受评估但被认为没有COPD的其他吸烟者中,共有56%的人也接受了转诊。在基层医疗中对长期疾病诊所就诊的人群进行症状评估和微型肺活量测定是可行的,并且在识别可能此前未被诊断出的COPD患者方面具有很高的检出率。