• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Age related changes in gut physiology and nutritional status.肠道生理和营养状况的年龄相关变化。
Gut. 1996 Mar;38(3):306-9. doi: 10.1136/gut.38.3.306.
2
Are gastrointestinal disorders in the elderly important?
J Clin Gastroenterol. 1993 Apr;16(3):186-8.
3
Facilitated feeding in disabled elderly.
Curr Opin Clin Nutr Metab Care. 2002 May;5(3):315-9. doi: 10.1097/00075197-200205000-00012.
4
Nutritional consequences of intestinal bacterial overgrowth.肠道细菌过度生长的营养后果。
Compr Ther. 1994;20(9):523-30.
5
Enteral feeding maintains but does not improve villous atrophy in malnourished patients.
J Nutr Health Aging. 1999;3(3):169-71.
6
Nutrition in the elderly.老年人的营养
Best Pract Res Clin Gastroenterol. 2001 Dec;15(6):869-84. doi: 10.1053/bega.2001.0246.
7
Geriatric nutrition.老年营养
Clin Geriatr Med. 1990 May;6(2):319-34.
8
The aging gut. Nutritional issues.
Gastroenterol Clin North Am. 1998 Jun;27(2):309-24. doi: 10.1016/s0889-8553(05)70005-4.
9
Ageing and muscle: the effects of malnutrition, re-nutrition, and physical exercise.
Curr Opin Clin Nutr Metab Care. 2001 Jul;4(4):295-300. doi: 10.1097/00075197-200107000-00009.
10
The ageing gastrointestinal tract.衰老的胃肠道。
Curr Opin Clin Nutr Metab Care. 2016 Jan;19(1):12-8. doi: 10.1097/MCO.0000000000000238.

引用本文的文献

1
Creatine monohydrate supplementation for older adults and clinical populations.一水肌酸对老年人及临床人群的补充作用。
J Int Soc Sports Nutr. 2025 Sep;22(sup1):2534130. doi: 10.1080/15502783.2025.2534130. Epub 2025 Jul 17.
2
The vitality domain of intrinsic capacity: A scoping review of conceptual frameworks and measurements.内在能力的活力领域:概念框架与测量的范围综述
J Frailty Aging. 2025 Aug;14(4):100058. doi: 10.1016/j.tjfa.2025.100058. Epub 2025 Jun 13.
3
A Review on In Vitro Evaluation of Chemical and Physical Digestion for Controlling Gastric Digestion of Food.关于化学和物理消化体外评估以控制食物胃消化的综述
Foods. 2025 Apr 21;14(8):1435. doi: 10.3390/foods14081435.
4
Assessing the gut microbiota composition in older adults: connections to physical activity and healthy ageing.评估老年人的肠道微生物群组成:与身体活动和健康衰老的联系。
Geroscience. 2025 Mar 17. doi: 10.1007/s11357-025-01605-w.
5
Comparing gastrointestinal dysfunction score and acute gastrointestinal injury grade for predicting short-term mortality in critically ill patients.比较胃肠道功能障碍评分和急性胃肠损伤分级对预测危重症患者短期死亡率的作用。
World J Gastroenterol. 2024 Nov 14;30(42):4523-4531. doi: 10.3748/wjg.v30.i42.4523.
6
Large gastric ulcer presenting as gastric pneumatosis.表现为胃积气的巨大胃溃疡。
BMJ Case Rep. 2023 Sep 18;16(9):e256724. doi: 10.1136/bcr-2023-256724.
7
Magnetic-controlled capsule endoscopy performance in aging patients.磁控胶囊内镜在老年患者中的应用性能。
BMC Gastroenterol. 2023 Aug 11;23(1):277. doi: 10.1186/s12876-023-02914-0.
8
Emerging epigenetic dynamics in gut-microglia brain axis: experimental and clinical implications for accelerated brain aging in schizophrenia.肠道-小胶质细胞-脑轴中新兴的表观遗传动力学:对精神分裂症加速脑老化的实验和临床意义
Front Cell Neurosci. 2023 May 15;17:1139357. doi: 10.3389/fncel.2023.1139357. eCollection 2023.
9
Efficiency of probiotics in elderly patients undergoing orthopedic surgery for postoperative cognitive dysfunction: a study protocol for a multicenter, randomized controlled trial.益生菌对老年骨科手术患者术后认知功能障碍的疗效:一项多中心、随机对照试验的研究方案。
Trials. 2023 Feb 25;24(1):146. doi: 10.1186/s13063-023-07167-6.
10
Microbiome assembly and maintenance across the lifespan of bumble bee workers.在熊蜂工蜂的整个生命周期中微生物组的组装和维持。
Mol Ecol. 2023 Feb;32(3):724-740. doi: 10.1111/mec.16769. Epub 2022 Nov 22.

本文引用的文献

1
THE EFFECT OF INCREASING AGE ON THE DISTRIBUTION OF PERIPHERAL BLOOD FLOW IN MAN.年龄增长对人体外周血流分布的影响。
J Am Geriatr Soc. 1965 Mar;13:192-8. doi: 10.1111/j.1532-5415.1965.tb02665.x.
2
Studies of basal and peak acid output with an augmented histamine test.通过增强组胺试验对基础胃酸分泌量和最大胃酸分泌量的研究。
Gut. 1963 Jun;4(2):136-44. doi: 10.1136/gut.4.2.136.
3
Exercise training and nutrient intake in elderly women.
J Am Diet Assoc. 1993 Jun;93(6):653-7. doi: 10.1016/0002-8223(93)91671-c.
4
Prolonged achlorhydria and gastric neoplasia: is there a causal relationship?
Gastroenterology. 1993 May;104(5):1554-7. doi: 10.1016/0016-5085(93)90370-r.
5
Duodenal brush-border mucosal glucose transport and enzyme activities in aging man and effect of bacterial contamination of the small intestine.老年男性十二指肠刷状缘黏膜葡萄糖转运及酶活性与小肠细菌污染的影响
Dig Dis Sci. 1993 Mar;38(3):403-9. doi: 10.1007/BF01316491.
6
Age- and gender-related differences in 24-hour esophageal pH monitoring of normal subjects.正常受试者24小时食管pH监测中的年龄和性别差异。
Dig Dis Sci. 1993 Oct;38(10):1926-8. doi: 10.1007/BF01296120.
7
The effects of bereavement on eating behaviors and nutrient intakes in elderly widowed persons.丧偶对老年丧偶者饮食行为和营养摄入的影响。
J Gerontol. 1993 Jul;48(4):S223-9. doi: 10.1093/geronj/48.4.s223.
8
Mouth dryness as reported by older Floridians.佛罗里达州老年人报告的口腔干燥情况。
Community Dent Oral Epidemiol. 1993 Dec;21(6):390-7. doi: 10.1111/j.1600-0528.1993.tb01105.x.
9
Changes in human jaw muscles with age and dental state.
Gerodontology. 1993 Jul;10(1):16-22. doi: 10.1111/j.1741-2358.1993.tb00074.x.
10
Influence of age on the secretory rates of the human minor salivary glands and whole saliva.年龄对人类小唾液腺及全唾液分泌率的影响。
Arch Oral Biol. 1993 Sep;38(9):755-61. doi: 10.1016/0003-9969(93)90071-s.

肠道生理和营养状况的年龄相关变化。

Age related changes in gut physiology and nutritional status.

作者信息

Lovat L B

机构信息

Department of Medicine, Hammersmith Hospital, London.

出版信息

Gut. 1996 Mar;38(3):306-9. doi: 10.1136/gut.38.3.306.

DOI:10.1136/gut.38.3.306
PMID:8675079
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1383055/
Abstract

Few gastrointestinal functions decline to an important extent as a result of old age alone and there is little clinical evidence that significant malnutrition occurs in any normal elderly person as a result of the aging process itself. Nevertheless, decreased gastrointestinal reserve makes older people highly sensitive to minor insults and decompensation can rapidly occur. Drugs appreciably affect taste sensation, which is already blunted and psychological as well as physical disability can have a major impact on appetite. Malabsorption can be caused by gastric hypochlorhydria with small bowel bacterial overgrowth and while gastrointestinal dysmotility can be caused by subclinical hypothyroidism, it can improve in response to physical exercise. Evidence is now mounting that thorough investigation of gastrointestinal disturbances in elderly patients coupled with intensive nutritional support can make a very real impact on their outcome. Gastroenterologists should therefore seek out and actively treat gastrointestinal disorders in the elderly and not just ascribe them to old age.

摘要

很少有胃肠道功能仅因年老就出现显著衰退,而且几乎没有临床证据表明任何正常老年人会因衰老过程本身而发生严重营养不良。然而,胃肠道储备功能下降使老年人对轻微损伤高度敏感,且很快会出现失代偿。药物会明显影响味觉,而味觉本就已迟钝,心理和身体残疾也会对食欲产生重大影响。胃酸过少伴小肠细菌过度生长可导致吸收不良,虽然亚临床甲状腺功能减退可引起胃肠动力障碍,但体育锻炼可使其改善。现在越来越多的证据表明,对老年患者的胃肠道紊乱进行全面调查并给予强化营养支持,可切实改善其预后。因此,胃肠病学家应找出并积极治疗老年人的胃肠道疾病,而不应仅仅将其归因于年老。