Drozdowski Laurie, Thomson Alan B R
World J Gastroenterol. 2009 Jan 28;15(4):385-406. doi: 10.3748/wjg.15.385.
There are various hormones and growth factors which may modify the intestinal absorption of nutrients, and which might thereby be useful in a therapeutic setting, such as in persons with short bowel syndrome. In part I, we focus first on insulin-like growth factors, epidermal and transferring growth factors, thyroid hormones and glucocorticosteroids. Part II will detail the effects of glucagon-like peptide (GLP)-2 on intestinal absorption and adaptation, and the potential for an additive effect of GLP2 plus steroids.
有多种激素和生长因子可能会改变营养物质的肠道吸收,因此在治疗环境中可能有用,比如在短肠综合征患者中。在第一部分,我们首先关注胰岛素样生长因子、表皮生长因子和转铁生长因子、甲状腺激素及糖皮质激素。第二部分将详细阐述胰高血糖素样肽(GLP)-2对肠道吸收及适应性的影响,以及GLP-2与类固醇联合使用产生相加效应的可能性。