Michel P L, Acar J, Chomette G, Iung B
Hopital Tenon, Cardiology Department, Paris, France.
Eur Heart J. 1991 Aug;12(8):875-82.
In view of the growing incidence of degenerative origin among the aetiologies of aortic regurgitation, we felt it interesting to report our experience of the surgical treatment of such patients. Out of 313 patients operated on for isolated chronic aortic regurgitation between 1974 and 1989, 102 (32.6%) had aortic regurgitation of degenerative origin and form the basis of this study. The patients were divided into group I (n = 48) without aneurysm of the ascending aorta and group II (54 patients) with anulo-aortic ectasia. The first group was further subdivided according to the diameter of the ascending aorta: in group Ia (23 patients) the aorta was normal with a root diameter of less than 40 mm, while in group Ib (25 patients) the aorta was enlarged (root diameter between 40 and 54 mm). There was no statistically significant difference between the pre-operative and operative parameters of patients in groups Ia and Ib. All underwent aortic valve replacement without associated surgery of the ascending aorta. During a mean follow-up of 58 months, five patients from group Ib had aortic dissection and in another three, an ascending aorta aneurysm developed. Reoperation was performed in six cases. No such complications occurred in group Ia. At 6 years, the proportion of patients free from complications related to the ascending aorta was 100% in group Ia vs 63 +/- 6% in group Ib (P less than 0.05). In group II, all the patients underwent aortic valve replacement. The modalities of repair of the ascending aorta differed with time.(ABSTRACT TRUNCATED AT 250 WORDS)
鉴于退行性病因在主动脉反流病因中所占比例日益增加,我们认为有必要报告我们对这类患者进行外科治疗的经验。在1974年至1989年间接受单纯慢性主动脉反流手术的313例患者中,102例(32.6%)患有退行性主动脉反流,构成本研究的基础。患者分为两组:I组(n = 48)升主动脉无动脉瘤,II组(54例)有主动脉瓣环扩张。I组又根据升主动脉直径进一步细分:Ia组(23例)主动脉正常,根部直径小于40 mm,而Ib组(25例)主动脉扩大(根部直径在40至54 mm之间)。Ia组和Ib组患者术前和手术参数无统计学显著差异。所有患者均接受主动脉瓣置换术,未同时进行升主动脉手术。在平均58个月的随访期间,Ib组有5例患者发生主动脉夹层,另有3例发生升主动脉瘤。6例患者接受了再次手术。Ia组未发生此类并发症。6年时,Ia组与升主动脉相关并发症-free患者比例为100%,而Ib组为63±6%(P<0.05)。II组所有患者均接受主动脉瓣置换术。升主动脉修复方式随时间而异。(摘要截于250字)