Maejima K, Nagase S
Japan Automobile Research Institute, Ibaraki.
Jikken Dobutsu. 1991 Jul;40(3):389-93. doi: 10.1538/expanim1978.40.3_389.
We investigated the effect of starvation for 24 hr and subsequent refeeding for 12 hr on the circadian rhythms of 39 hematological and clinico-biochemical parameters, and water intake of F344 rats. The rats scarcely drank any water during the starvation period, but subsequently their intake of water were normal, even in the light period. During starvation, 12 parameters such as serum levels of alkaline phosphatase activity and PaCO2 decreased with time-related and time-related increases of 8 parameters such as the erythrocyte count and cholinesterase activity. During refeeding for 12 hr, almost all these biochemical parameters were normalized, but none of the hematological values except the leukocyte count returned to normal levels. Starvation and refeeding had little affect on the circadian rhythms of others.
我们研究了禁食24小时及随后再喂食12小时对F344大鼠39项血液学和临床生化参数的昼夜节律以及水摄入量的影响。在禁食期间，大鼠几乎不饮水，但随后即使在光照期，它们的水摄入量也正常。禁食期间，血清碱性磷酸酶活性和动脉血二氧化碳分压等12项参数随时间下降，而红细胞计数和胆碱酯酶活性等8项参数则随时间增加。再喂食12小时期间，几乎所有这些生化参数都恢复正常，但除白细胞计数外，没有一项血液学指标恢复到正常水平。禁食和再喂食对其他指标的昼夜节律影响很小。
