Gomez Cerezo J, Codoceo R, Fernandez Calle P, Molina F, Tenias J M, Vazquez J J
Department of Internal Medicine, Hospital La Paz, Madrid, Spain.
Digestion. 1991;48(3):134-40. doi: 10.1159/000200685.
We have investigated the relationship between cholecystokinin levels and abdominal pain in patients with chronic pancreatitis. The baseline and postprandial cholecystokinin levels were measured in 15 patients with chronic pancreatitis (8 with and 7 without abdominal pain) and in a reference group of 8 healthy subjects. The baseline, 30 and 60 min postprandial plasma cholecystokinin levels were significantly (p less than 0.05) higher in the patients with pain as compared with the other two groups. No correlation was observed between increased cholecystokinin levels and impairment of the exocrine pancreatic function as assessed by the NBT-PABA test. The increased cholecystokinin levels might be an important factor in the genesis of pain in chronic pancreatitis.
我们研究了慢性胰腺炎患者胆囊收缩素水平与腹痛之间的关系。对15例慢性胰腺炎患者（8例有腹痛，7例无腹痛）以及8名健康受试者组成的参照组测定了基线及餐后胆囊收缩素水平。与其他两组相比，有疼痛的患者其基线、餐后30分钟和60分钟的血浆胆囊收缩素水平显著更高（p<0.05）。通过NBT - PABA试验评估，未观察到胆囊收缩素水平升高与胰腺外分泌功能损害之间存在相关性。胆囊收缩素水平升高可能是慢性胰腺炎疼痛发生的一个重要因素。
