Schafmayer A, Becker H D, Werner M, Fölsch U R, Creutzfeldt W
Digestion. 1985;32(2):136-9. doi: 10.1159/000199231.
Using a sensitive and specific radioimmunoassay for cholecystokinin (CCK) we have measured plasma CCK levels in patients with and without chronic pancreatitis. All patients suffered from steatorrhea. The basal plasma values in patients with chronic pancreatitis (n = 10) were significantly higher compared with a control group of 40 normal subjects. After ingestion of a test meal peak plasma levels of CCK were significantly higher than in controls, but the integrated CCK release did not differ from the normal subjects. The findings indicate a close relationship between plasma CCK concentration and exocrine pancreatic function.
我们使用一种灵敏且特异的胆囊收缩素（CCK）放射免疫分析法，对患有和未患慢性胰腺炎的患者血浆CCK水平进行了测定。所有患者均有脂肪泻。10例慢性胰腺炎患者的基础血浆值与40名正常受试者的对照组相比显著更高。摄入试验餐后，CCK的血浆峰值水平显著高于对照组，但CCK的综合释放量与正常受试者并无差异。这些发现表明血浆CCK浓度与胰腺外分泌功能之间存在密切关系。
