Han Xiao-Li, Zhang Xiao-Bo, Guo Lan-Ping, Huang Lu-Qi, Li Ming-Jing, Liu Xiu-Hua, Sun Yu-Zhang, Lv Jin-Rong
Key Lab of Natural Drug and Immune Engineering, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475001, China.
Zhongguo Zhong Yao Za Zhi. 2008 Sep;33(18):2041-8.
To analyze the residues of heavy metals in Chinese crude drugs.
The SPSS 13.0 software was used to analyze the data of Cu, Pb, As, Cd, Hg collected in literatures. And, Green Trade Standards of Importing & Exporting Medicinal Plants & Preparations was used as the standard to evaluate the pollution condition of Cu, Pb, As, Cd, Hg in Chinese crude drugs.
Chinese crude drugs were contaminated by heavy metals in different levels. The content of Cu, Pb, As, Cd, Hg exceeded the limit of the standard and the percentage was 21.0%, 12.0%, 9.7%, 28.5%, 6.9%, respectively; the phenomena of two, three and four metals exceeding limited standard simultaneity in a drug were also found and the percentage was 4.6%, 1.5%, 0.7%, respectively; the content of heavy metals in Radix Platycodi, Radix Asari and Rhizoma Coptidis was higher among the thirty-six Chinese crude drugs; All of the content of five heavy metals in Barbary Fructus Lycii Rhizoma Anemones Raddeanae, Radix Panacis Quiquefolii and Fructus Aurantii were below the limit; The pollution levels of heavy metals in different locality were different; The content of Cu, Pb in cultivated Chinese crude drugs was higher than that in wild Chinese crude drugs, while the content of As in wild Chinese crude drugs was higher than that in cultivated Chinese crude drugs.
The pollution levels of heavy metals in Chinese crude drugs were detailed reported in this paper. And it provided ways for the further study of heavy metals in Chinese crude drugs.
分析中药材中重金属残留情况。
运用SPSS 13.0软件对文献中收集的铜、铅、砷、镉、汞数据进行分析。并以《进出口中药材及其制剂绿色行业标准》为标准，评价中药材中铜、铅、砷、镉、汞的污染状况。
中药材受到不同程度的重金属污染。铜、铅、砷、镉、汞含量超标，超标率分别为21.0%、12.0%、9.7%、28.5%、6.9%；还发现一种药材中有两种、三种和四种金属同时超标现象，超标率分别为4.6%、1.5%、0.7%；在36种中药材中，桔梗、细辛和黄连的重金属含量较高；地骨皮、白头翁、西洋参和枳壳中5种重金属含量均未超标；不同产地的重金属污染程度不同；栽培中药材中铜、铅含量高于野生中药材，而野生中药材中砷含量高于栽培中药材。
本文详细报道了中药材中重金属的污染程度。为进一步研究中药材中的重金属提供了途径。
