Martinez-Madrigal F, Casiraghi O, Khattech A, Nasr-Khattech R B, Richard J M, Micheau C
Department of Histopathology A, Institut Gustave-Roussy, Villejuif, France.
Hum Pathol. 1991 Sep;22(9):929-31. doi: 10.1016/0046-8177(91)90186-s.
A hypopharyngeal squamous-cell carcinoma with sebaceous differentiation is reported. In the primary as well as the metastatic lymph nodes, the tumor showed basaloid, squamous, and sebaceous cells. In addition, immunostaining for S-100 protein and vimentin manifested scattered cells showing cytoplasmic processes suggesting myoepithelial cells. An exhaustive review of the literature revealed only one similar case previously reported. The probable origin from the minor salivary glands is discussed.
报告了1例具有皮脂腺分化的下咽鳞状细胞癌。在原发灶以及转移淋巴结中，肿瘤呈现基底样细胞、鳞状细胞和皮脂腺细胞。此外，S-100蛋白和波形蛋白免疫染色显示散在细胞有细胞质突起，提示为肌上皮细胞。对文献进行详尽检索发现此前仅报道过1例类似病例。文中讨论了其可能起源于小唾液腺的情况。
