Becerril Héctor A, Woolley Adam T
Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602, USA.
Chem Soc Rev. 2009 Feb;38(2):329-37. doi: 10.1039/b718440a. Epub 2008 Nov 26.
Nanofabrication, or the organizational control over matter at the nanometre scale, is an intriguing scientific challenge requiring multidisciplinary tools for its solution. DNA is a biomolecule that can be combined with other nanometre-scale entities through chemical self-assembly to form a broad variety of nanomaterials. In this tutorial review we present the principles that allow DNA to interact with other chemical species, and describe the challenges and potential applications of DNA as a template for making both biological and inorganic features with nanometre resolution. As such, this report should be of interest to chemists, surface and materials scientists, biologists, and nanotechnologists, as well as others who seek to use DNA in nanofabrication.
纳米制造，即对纳米尺度物质的组织控制，是一项极具吸引力的科学挑战，需要多学科工具来解决。DNA是一种生物分子，它可以通过化学自组装与其他纳米尺度的实体结合，形成各种各样的纳米材料。在本教程综述中，我们阐述了使DNA与其他化学物种相互作用的原理，并描述了将DNA用作模板以制备具有纳米分辨率的生物和无机特征所面临的挑战及潜在应用。因此，本报告对于化学家、表面和材料科学家、生物学家、纳米技术专家以及其他试图在纳米制造中使用DNA的人来说应该是有意义的。
