Han Jie, Liu Yan, Guo Rong
School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, 225002, Jiangsu, PR China.
J Am Chem Soc. 2009 Feb 18;131(6):2060-1. doi: 10.1021/ja808935n.
We have demonstrated that poly(2-aminothiophenol)-stablized gold nanoparticles with proper gold size and polymer thickness are active catalysts for Suzuki-Miyaura cross-coupling reaction of aryl halides with arylboronic acids in water and air for the first time. High yields can be obtained with aryl halides or arylboronic acids bearing a variety of substituents. This new finding will undoubtedly broaden the application of gold nanoparticles in organic catalytic reactions.
我们首次证明，具有合适金尺寸和聚合物厚度的聚（2-氨基硫酚）稳定的金纳米颗粒是芳基卤化物与芳基硼酸在水和空气中进行铃木-宫浦交叉偶联反应的活性催化剂。带有各种取代基的芳基卤化物或芳基硼酸都能获得高产率。这一新发现无疑将拓宽金纳米颗粒在有机催化反应中的应用。
