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银屑病患者的生活质量:一项来自印度南部的研究。

Quality of life in psoriasis: a study from south India.

作者信息

Rakhesh S V, D'Souza Mariette, Sahai Ajith

机构信息

Department of Dermatology and STD, Academy of Medical Sciences, Kannur, Kerala, India.

出版信息

Indian J Dermatol Venereol Leprol. 2008 Nov-Dec;74(6):600-6. doi: 10.4103/0378-6323.45101.

Abstract

BACKGROUND

Psoriasis can have a profound impact on a patient's quality of life. Very few Indian studies have examined this aspect of Indian patients of psoriasis.

AIMS

This study was conducted to assess the clinical severity, as well as physical and psychosocial disability, and stress incurred and to analyze their interrelationship in psoriasis patients aged more than 18 years.

METHODS

This hospital-based cross-sectional study was conducted in the Department of Dermatology, JIPMER, Pondicherry, India. Clinical severity, physical and psychosocial morbidity, and the stress incurred were measured using psoriasis area severity index (PASI), psoriasis disability index (PDI), and psoriasis life stress inventory (PLSI) respectively, the latter two of which were suitably modified and translated into the local language, viz., Tamil. Appropriate tests were conducted using SPSS for Windows (Release 7.5.1) statistical software.

RESULTS

Fifty patients (34 males, 16 females) were included in the study. The clinical PASI scores correlated significantly with the overall physical disability (PDI), individual aspects of the PDI (except the treatment-related activities), and the measurement of stress incurred (PLSI). A PASI score of more than 18 delineated a subgroup of patients with higher overall physical disability and higher stress rating. Among the physical and psychosocial factors investigated, daily activities, employment, and treatment were reported to be affected the most. Psoriasis sufferers are also most likely to feel self-conscious, be disturbed / inconvenienced by the shedding of the skin, live in a constant fear of relapse, and avoid social interactions.

CONCLUSIONS

The present study provides compelling evidence that psoriasis affects the quality of life, and it highlights the importance of adopting a multidimensional assessment of psoriasis.

摘要

背景

银屑病会对患者的生活质量产生深远影响。很少有印度的研究探讨印度银屑病患者的这一方面。

目的

本研究旨在评估18岁以上银屑病患者的临床严重程度、身体和心理社会残疾情况以及所承受的压力,并分析它们之间的相互关系。

方法

本基于医院的横断面研究在印度本地治里JIPMER的皮肤科进行。分别使用银屑病面积严重指数(PASI)、银屑病残疾指数(PDI)和银屑病生活压力量表(PLSI)来测量临床严重程度、身体和心理社会发病率以及所承受的压力,后两者经过适当修改并翻译成当地语言泰米尔语。使用适用于Windows的SPSS(版本7.5.1)统计软件进行适当的测试。

结果

50名患者(34名男性,16名女性)纳入研究。临床PASI评分与总体身体残疾(PDI)、PDI的各个方面(治疗相关活动除外)以及所承受压力的测量(PLSI)显著相关。PASI评分超过18分界定了一组总体身体残疾程度较高且压力评分较高的患者亚组。在所调查的身体和心理社会因素中,日常活动、就业和治疗受影响最大。银屑病患者也最容易感到难为情,因皮肤脱屑而受到困扰/不便,一直担心复发,并避免社交互动。

结论

本研究提供了令人信服的证据,表明银屑病会影响生活质量,并强调了对银屑病采用多维评估的重要性。

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